通过树形演化结构学习生物特征原型,发现跨物种的进化共性。
What Do You See in Common? Learning Hierarchical Prototypes over Tree-of-Life to Discover Evolutionary Traits
- 基于演化树结构设计分层原型网络,避免内部节点原型过专
- 在多个数据集上实现更高准确率与泛化能力,优于基线方法
- 适合研究生物演化、图像特征提取的学者使用
生物学中的一个重大挑战是发现进化特征——即在具有共同祖先的物种群中普遍存在的生物特征。随着生物图像库的不断增长,直接从图像中发现具有层次结构的进化特征成为可能。然而,现有基于原型的方法多适用于扁平类别结构,在发现分层原型时面临内部节点原型过专等问题。为此,本文提出层级对齐共性原型网络(HComP-Net),其关键创新包括:一种新型过专性损失以避免内部节点学习到过专原型;一种新型判别性损失,确保某节点原型不在不同谱系的对比物种中出现;以及一种掩码模块,可在不损害分类性能的前提下排除高层级的过专原型。实验表明,相比基线方法,HComP-Net学习到的原型更具准确性、语义一致性,并能泛化至未见物种。
原文摘要 · Abstract (English)
A grand challenge in biology is to discover evolutionary traits - features of organisms common to a group of species with a shared ancestor in the tree of life (also referred to as phylogenetic tree). With the growing availability of image repositories in biology, there is a tremendous opportunity to discover evolutionary traits directly from images in the form of a hierarchy of prototypes. However, current prototype-based methods are mostly designed to operate over a flat structure of classes and face several challenges in discovering hierarchical prototypes, including the issue of learning over-specific prototypes at internal nodes. To overcome these challenges, we introduce the framework of Hierarchy aligned Commonality through Prototypical Networks (HComP-Net). The key novelties in HComP-Net include a novel over-specificity loss to avoid learning over-specific prototypes, a novel discriminative loss to ensure prototypes at an internal node are absent in the contrasting set of species with different ancestry, and a novel masking module to allow for the exclusion of over-specific prototypes at higher levels of the tree without hampering classification performance. We empirically show that HComP-Net learns prototypes that are accurate, semantically consistent, and generalizable to unseen species in comparison to baselines.
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