用视觉语言模型和运动感知Mamba预测手部轨迹，兼顾时序合理性和实时性。

Understanding human intentions and actions through egocentric videos is important on the path to embodied artificial intelligence. As a branch of egocentric vision techniques, hand trajectory prediction plays a vital role in comprehending human motion patterns, benefiting downstream tasks in extended reality and robot manipulation. However, capturing high-level human intentions consistent with reasonable temporal causality is challenging when only egocentric videos are available. This difficulty is exacerbated under camera egomotion interference and the absence of affordance labels to explicitly guide the optimization of hand waypoint distribution. In this work, we propose a novel hand trajectory prediction method dubbed MADiff, which forecasts future hand waypoints with diffusion models. The devised denoising operation in the latent space is achieved by our proposed motion-aware Mamba, where the camera wearer's egomotion is integrated to achieve motion-driven selective scan (MDSS). To discern the relationship between hands and scenarios without explicit affordance supervision, we leverage a foundation model that fuses visual and language features to capture high-level semantics from video clips. Comprehensive experiments conducted on five public datasets with the existing and our proposed new evaluation metrics demonstrate that MADiff predicts comparably reasonable hand trajectories compared to the state-of-the-art baselines, and achieves real-time performance. We will release our code and pretrained models of MADiff at the project page: https://irmvlab.github.io/madiff.github.io.