用视觉语言模型检测深度伪造，无需训练就能跨数据集有效识别。

The proliferation of deepfake faces poses huge potential negative impacts on our daily lives. Despite substantial advancements in deepfake detection over these years, the generalizability of existing methods against forgeries from unseen datasets or created by emerging generative models remains constrained. In this paper, inspired by the zero-shot advantages of Vision-Language Models (VLMs), we propose a novel approach that repurposes a well-trained VLM for general deepfake detection. Motivated by the model reprogramming paradigm that manipulates the model prediction via input perturbations, our method can reprogram a pre-trained VLM model (e.g., CLIP) solely based on manipulating its input without tuning the inner parameters. First, learnable visual perturbations are used to refine feature extraction for deepfake detection. Then, we exploit information of face embedding to create sample-level adaptative text prompts, improving the performance. Extensive experiments on several popular benchmark datasets demonstrate that (1) the cross-dataset and cross-manipulation performances of deepfake detection can be significantly and consistently improved (e.g., over 88\% AUC in cross-dataset setting from FF++ to WildDeepfake); (2) the superior performances are achieved with fewer trainable parameters, making it a promising approach for real-world applications.