用深度学习精准识别血管内OCT图像中的粥样斑块帽,助力心脏病风险预测。
FiAt-Net: Detecting Fibroatheroma Plaque Cap in 3D Intravascular OCT Images
- 基于多头自注意力融合多尺度图像特征,提升斑块帽检测精度。
- 通过二值分割缓解数据分布不均问题,在3D IVOCT数据上表现优异。
- 适合心血管影像分析、医学图像算法研究者参考。
冠状动脉疾病(CAD)的关键表现是纤维粥样硬化斑块的形成,其帽状结构可能破裂,导致冠状动脉阻塞和心肌梗死。因此,对冠状动脉斑块及其帽状结构的定量分析,以及评估其破裂风险,对判断心血管事件至关重要。本文提出一种名为FiAt-Net的深度学习方法,用于在3D血管内光学相干断层扫描(IVOCT)图像中检测纤维粥样硬化(FA)的弧长范围并分割其帽状结构。首先将IVOCT的2D图像帧关联至不同簇,每个簇的数据用于模型训练。由于斑块通常局灶性分布且不均匀,采用二值分割方法识别FA区域,以缓解数据不平衡问题。此外,生成辅助图像以捕捉IVOCT强度变化,帮助区分冠状动脉壁上的FA与非FA区域。从原始IVOCT图像和辅助图像中提取多尺度信息,并使用多头自注意力机制进行融合。所提出的FiAt-Net在3D IVOCT冠状动脉图像数据集上表现出色,验证了其在准确检测FA帽方面的有效性。
原文摘要 · Abstract (English)
The key manifestation of coronary artery disease (CAD) is development of fibroatheromatous plaque, the cap of which may rupture and subsequently lead to coronary artery blocking and heart attack. As such, quantitative analysis of coronary plaque, its plaque cap, and consequently the cap's likelihood to rupture are of critical importance when assessing a risk of cardiovascular events. This paper reports a new deep learning based approach, called FiAt-Net, for detecting angular extent of fibroatheroma (FA) and segmenting its cap in 3D intravascular optical coherence tomography (IVOCT) images. IVOCT 2D image frames are first associated with distinct clusters and data from each cluster are used for model training. As plaque is typically focal and thus unevenly distributed, a binary partitioning method is employed to identify FA plaque areas to focus on to mitigate the data imbalance issue. Additional image representations (called auxiliary images) are generated to capture IVOCT intensity changes to help distinguish FA and non-FA areas on the coronary wall. Information in varying scales is derived from the original IVOCT and auxiliary images, and a multi-head self-attention mechanism is employed to fuse such information. Our FiAt-Net achieved high performance on a 3D IVOCT coronary image dataset, demonstrating its effectiveness in accurately detecting FA cap in IVOCT images.
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