用深度学习自动识别白血球类型,准确率超99%
Automatic Classification of White Blood Cell Images using Convolutional Neural Network
- 基于预训练CNN模型构建分类框架,提升白血球识别精度
- 在Kaggle和LISC数据集上分别达到99.57%和98.67%准确率
- 适合医学图像分析、自动化病理诊断领域研究人员参考
人体免疫系统中的白血球是多种疾病(如细菌感染、艾滋病、癌症、脾脏病变等)的重要指示物。白血球按核结构、形态和胞浆特征可分为四类:单核细胞、淋巴细胞、嗜酸性粒细胞和中性粒细胞。传统实验室中,病理学家通过显微镜手动分析并分类,耗时且易出错。因此亟需自动化方案。本文首先采用ResNet-50、InceptionV3、VGG16和MobileNetV2等预训练CNN模型对Kaggle公开的显微图像数据集进行分类,取得92%至95%的合理准确率。为进一步提升性能,受上述架构启发,提出一种新CNN框架,用于四类白血球的自动分类。该模型在Kaggle和LISC数据集上分别达到99.57%和98.67%的准确率,具备良好泛化能力,优于文献中已有结果。
原文摘要 · Abstract (English)
Human immune system contains white blood cells (WBC) that are good indicator of many diseases like bacterial infections, AIDS, cancer, spleen, etc. White blood cells have been sub classified into four types: monocytes, lymphocytes, eosinophils and neutrophils on the basis of their nucleus, shape and cytoplasm. Traditionally in laboratories, pathologists and hematologists analyze these blood cells through microscope and then classify them manually. This manual process takes more time and increases the chance of human error. Hence, there is a need to automate this process. In this paper, first we have used different CNN pre-train models such as ResNet-50, InceptionV3, VGG16 and MobileNetV2 to automatically classify the white blood cells. These pre-train models are applied on Kaggle dataset of microscopic images. Although we achieved reasonable accuracy ranging between 92 to 95%, still there is need to enhance the performance. Hence, inspired by these architectures, a framework has been proposed to automatically categorize the four kinds of white blood cells with increased accuracy. The aim is to develop a convolution neural network (CNN) based classification system with decent generalization ability. The proposed CNN model has been tested on white blood cells images from Kaggle and LISC datasets. Accuracy achieved is 99.57% and 98.67% for both datasets respectively. Our proposed convolutional neural network-based model provides competitive performance as compared to previous results reported in literature.
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