用神经隐式表示提升稀疏视角光声成像质量
Implicit Neural Representation for Sparse-view Photoacoustic Computed Tomography
- 用MLP将初始热分布建模为连续函数,避免离散化误差
- 自监督训练使重建图像在仿真与实验中均保持高保真度
- 适合追求高质量重建的医学成像研究者使用
光声计算机断层成像(PACT)通常需要高通道数系统以实现密集空间采样,防止混叠伪影。为降低系统复杂性,已有基于模型和深度学习的方法用于缓解稀疏视角采集带来的伪影。然而,这些方法在离散框架下求解,易受测量误差、离散化误差影响,且问题病态性随离散化分辨率上升。本文提出一种隐式神经表示(INR)框架,用于环形探头阵列的PACT图像重建。特别地,初始热分布被建模为空间坐标的连续函数,由多层感知机(MLP)实现。通过最小化实测与模型预测光声信号间的误差,在自监督方式下训练网络权重。训练完成后,输入坐标即可生成光声图像。仿真与体模实验表明,该方法在相同采集条件下,相比通用反投影法与基于模型的方法,显著提升了图像保真度并抑制了伪影。
原文摘要 · Abstract (English)
High-quality imaging in photoacoustic computed tomography (PACT) usually requires a high-channel count system for dense spatial sampling around the object to avoid aliasing-related artefacts. To reduce system complexity, various image reconstruction approaches, such as model-based (MB) and deep learning based methods, have been explored to mitigate the artefacts associated with sparse-view acquisition. However, the explored methods formulated the reconstruction problem in a discrete framework, making it prone to measurement errors, discretization errors, and the extend of the ill-poseness of the problem scales with the discretization resolution. In this work, an implicit neural representation (INR) framework is proposed for image reconstruction in PACT with ring transducer arrays to address these issues. pecially, the initial heat distribution is represented as a continuous function of spatial coordinates using a multi-layer perceptron (MLP). The weights of the MLP are then determined by a training process in a self-supervised manner, by minimizing the errors between the measured and model predicted PA signals. After training, PA images can be mapped by feeding the coordinates to the network. Simulation and phantom experiments showed that the INR method performed best in preserving image fidelity and in artefacts suppression for the same acquisition condition, compared to universal back-projection and MB methods.
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