通过波速模型优化,实现超声成像中散焦的局部精准校正。
Self-Portrait of the Focusing Process in Speckle: II. Gouy Phase Shift for Defocus Correction and Pixel Depth Reassignment
- 利用波速模型变化时的自画像特征,提取相位变化信息。
- 在组织模拟体模与活体肝脏数据中验证,实现像素级聚焦补偿。
- 适用于超声等回波定位成像,提升深度测量精度。
本系列论文第二篇探讨了利用散斑特性进行反射成像中的像差校正与回波延迟补偿。当波探测非均匀介质时,短尺度异质性引发随机干涉形成散斑,而长尺度波速波动会扭曲聚焦波前,导致图像像差。本文揭示了波的自画像随波速模型的变化规律,发现当波速模型最优时会出现显著的戈伊相位跃变。该敏感特征可用于:(i) 对图像每个像素独立优化波速模型;(ii) 实现全视场内局部精细的散焦补偿,有效消除大部分像差。实验在组织模拟体模及数值仿真中验证方法有效性,并应用于一位难成像患者的活体肝脏数据。波速优化使轴向像差得以补偿,并将单次散射回波重新映射至散射体真实位置。由于距离测量对诊断至关重要,此类波速优化对超声乃至所有基于回波定位原理的成像技术均具关键意义。
原文摘要 · Abstract (English)
This is the second article in a series of three dealing with the exploitation of speckle for aberration correction and reverberation compensation in reflection imaging. When probing heterogeneous media with waves, we have to cope with multi-scale fluctuations of the wave velocity. On the one hand, short-scale heterogeneities induce back-scattered echoes whose random interference generate a speckle pattern on the beamformed image. On the other hand, large-scale fluctuations of the wave-velocity can distort the focused wave-fronts, resulting in aberrations on the same image. In this paper, we show how the self-portrait of the wave evolves as a function of the speed-of-sound model. Strikingly, a Gouy phase shift is observed when the speed-of-sound model is optimal. This particularly sensitive feature enables: (i) an optimization of the speed-of-sound model for each pixel of the image; (ii) a local and fine compensation of defocus across the field-of-view, thereby compensating for most aberrations in the image. Experiment in a tissue-mimicking phantom and numerical simulations are first presented to validate our method. It is then applied to in-vivo liver data of a difficult-to-image patient. The speed-of-sound optimization allows an axial compensation of aberrations and a depth-reassignment of each singly-scattered echo to the actual position of the associated scatterer. As distance measurement is often critical for diagnosis, such a wave speed optimization can be crucial for ultrasound but also for any other imaging methods based on the principle of echo-location.
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