用改进的Swin-UNet模型实现跨器官跨扫描仪腺癌分割,提升病理图像分析鲁棒性。
Adenocarcinoma Segmentation Using Pre-trained Swin-UNet with Parallel Cross-Attention for Multi-Domain Imaging
- 基于预训练Swin-UNet,引入并行交叉注意力模块增强特征融合能力
- 在跨器官和跨扫描仪数据上分别取得0.7469和0.7597的分割分数
- 适用于多源病理图像,尤其适合临床实际中设备与组织差异场景
计算机辅助病理分析已成为肿瘤诊断的标准方法,但组织学图像中存在显著的域偏移问题,由解剖结构差异、组织制备流程及成像过程变化引起,严重影响分割模型的鲁棒性。本文提出一种基于预训练编码器的Swin-UNet框架,通过引入并行交叉注意力模块,有效应对不同器官与扫描仪间的腺癌分割挑战,同时考虑形态学变化与扫描仪带来的域差异。在跨器官与跨扫描仪腺癌分割挑战赛数据集上的实验表明,该框架在最终测试集上分别达到0.7469(跨器官)和0.7597(跨扫描仪)的分割分数,能有效适应多样成像条件,显著提升跨域分割精度。
原文摘要 · Abstract (English)
Computer aided pathological analysis has been the gold standard for tumor diagnosis, however domain shift is a significant problem in histopathology. It may be caused by variability in anatomical structures, tissue preparation, and imaging processes challenges the robustness of segmentation models. In this work, we present a framework consist of pre-trained encoder with a Swin-UNet architecture enhanced by a parallel cross-attention module to tackle the problem of adenocarcinoma segmentation across different organs and scanners, considering both morphological changes and scanner-induced domain variations. Experiment conducted on Cross-Organ and Cross-Scanner Adenocarcinoma Segmentation challenge dataset showed that our framework achieved segmentation scores of 0.7469 for the cross-organ track and 0.7597 for the cross-scanner track on the final challenge test sets, and effectively navigates diverse imaging conditions and improves segmentation accuracy across varying domains.
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