Mamba模型在医学影像分析中展现高效长序列处理能力,有望替代传统Transformer。
A Comprehensive Survey of Mamba Architectures for Medical Image Analysis: Classification, Segmentation, Restoration and Beyond
- 用线性复杂度的Mamba替代Transformer,解决长序列计算瓶颈
- 在多模态融合与图像分割任务中表现优于传统方法
- 适合需要快速推理的临床场景,如实时诊断与大规模数据处理
Mamba作为状态空间模型(SSM)的一种特殊形式,正成为医学图像分析中替代传统模板深度学习方法的新选择。尽管Transformer具有强大建模能力,但其二次计算复杂度及对长程依赖建模效率低下,限制了其在包含大量时空关系的大规模医学数据中的应用。相比之下,Mamba具备线性时间复杂度,无需注意力机制即可处理更长序列,实现更快推理和更低内存占用。它在多模态数据融合方面表现出色,提升了诊断准确率和患者预后评估。本文系统梳理了SSM核心概念(如S4、S5、S6)及其在医学影像中的演化路径,涵盖纯Mamba、U-Net变体、与CNN、Transformer及图神经网络的混合模型。同时讨论了优化技术、适配策略、常用数据集、典型应用场景与实验结果,并展望其挑战与未来方向。文中总结的全部医学领域Mamba架构列表可在GitHub获取。
原文摘要 · Abstract (English)
Mamba, a special case of the State Space Model, is gaining popularity as an alternative to template-based deep learning approaches in medical image analysis. While transformers are powerful architectures, they have drawbacks, including quadratic computational complexity and an inability to address long-range dependencies efficiently. This limitation affects the analysis of large and complex datasets in medical imaging, where there are many spatial and temporal relationships. In contrast, Mamba offers benefits that make it well-suited for medical image analysis. It has linear time complexity, which is a significant improvement over transformers. Mamba processes longer sequences without attention mechanisms, enabling faster inference and requiring less memory. Mamba also demonstrates strong performance in merging multimodal data, improving diagnosis accuracy and patient outcomes. The organization of this paper allows readers to appreciate the capabilities of Mamba in medical imaging step by step. We begin by defining core concepts of SSMs and models, including S4, S5, and S6, followed by an exploration of Mamba architectures such as pure Mamba, U-Net variants, and hybrid models with convolutional neural networks, transformers, and Graph Neural Networks. We also cover Mamba optimizations, techniques and adaptations, scanning, datasets, applications, experimental results, and conclude with its challenges and future directions in medical imaging. This review aims to demonstrate the transformative potential of Mamba in overcoming existing barriers within medical imaging while paving the way for innovative advancements in the field. A comprehensive list of Mamba architectures applied in the medical field, reviewed in this work, is available at Github.
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