针对深肤色患者慢性伤口分割,提出改进的混合网络模型。
An Enhanced Harmonic Densely Connected Hybrid Transformer Network Architecture for Chronic Wound Segmentation Utilising Multi-Colour Space Tensor Merging
- 引入多色空间张量融合与对比抑制模块增强特征学习
- 在深肤色测试集上Dice系数提升0.1221,交并比提升0.1274
- 首次聚焦深肤色伤口分割,适合医疗图像分析与跨种族研究
慢性伤口及其并发症正给全球医疗机构带来日益沉重负担。静脉性、动脉性、糖尿病性及压疮在全球范围愈发普遍,可导致严重后果,如截肢和感染引发的死亡率上升。因此,开发辅助临床决策的新方法至关重要。本文提出一种改进的HarDNet分割架构,通过在网络初始层加入对比消除组件以增强特征提取能力,并采用多色空间张量融合策略,同时调整卷积块的谐波结构以支持新特征。模型仅用浅肤色患者伤口图像训练,在两个测试集(一个带真实标签,一个无)上评估,后者均为深肤色案例。通过临床专家主观评分并使用组内相关系数评估一致性。在有真实标签的深肤色测试集上,Dice相似系数提升0.1221,交并比提升0.1274。定性分析显示专家评分显著提高,较基线模型改善超3%。本研究是首个仅基于浅肤色数据训练却聚焦深肤色伤口分割的工作。糖尿病在深肤色人群高发,凸显对此类病例的关注必要性。此外,本研究也是迄今规模最大的慢性伤口分割定性评估。
原文摘要 · Abstract (English)
Chronic wounds and associated complications present ever growing burdens for clinics and hospitals world wide. Venous, arterial, diabetic, and pressure wounds are becoming increasingly common globally. These conditions can result in highly debilitating repercussions for those affected, with limb amputations and increased mortality risk resulting from infection becoming more common. New methods to assist clinicians in chronic wound care are therefore vital to maintain high quality care standards. This paper presents an improved HarDNet segmentation architecture which integrates a contrast-eliminating component in the initial layers of the network to enhance feature learning. We also utilise a multi-colour space tensor merging process and adjust the harmonic shape of the convolution blocks to facilitate these additional features. We train our proposed model using wound images from light-skinned patients and test the model on two test sets (one set with ground truth, and one without) comprising only darker-skinned cases. Subjective ratings are obtained from clinical wound experts with intraclass correlation coefficient used to determine inter-rater reliability. For the dark-skin tone test set with ground truth, we demonstrate improvements in terms of Dice similarity coefficient (+0.1221) and intersection over union (+0.1274). Qualitative analysis showed high expert ratings, with improvements of >3% demonstrated when comparing the baseline model with the proposed model. This paper presents the first study to focus on darker-skin tones for chronic wound segmentation using models trained only on wound images exhibiting lighter skin. Diabetes is highly prevalent in countries where patients have darker skin tones, highlighting the need for a greater focus on such cases. Additionally, we conduct the largest qualitative study to date for chronic wound segmentation.
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