用图表示学习分析神经网络的结构与动态关系,揭示其内在关联。
Network Representation Learning for Biophysical Neural Network Analysis
- 基于计算图构建神经网络表征,捕捉信息流与结构关系
- 引入生物启发注意力网络,实现多尺度相关性分析
- 首个系统应用表示学习于完整生物神经网络分析
生物物理神经网络(BNN)的分析是计算神经科学长期关注的重点。核心挑战在于解析神经元与突触动态、连接模式及学习过程之间的复杂关联。本文提出一种基于网络表示学习(NRL)的新框架,利用注意力得分揭示网络组件及其特征间的深层关联。该框架整合了基于计算图(CG)的BNN表示、生物启发图注意力网络(BGAN),以及一个大规模公开的BNN数据集。CG表示捕捉关键计算特征、信息流和结构关系;BGAN反映神经元的组成结构(如树突、胞体、轴突)及组件间双向信息流。数据集包含来自ModelDB的公开模型,经Python重建并标准化为NeuroML格式,并补充了经典神经元与突触模型的数据。据我们所知,这是首次将基于NRL的方法应用于完整BNN及其分析的系统性研究。
原文摘要 · Abstract (English)
The analysis of biophysical neural networks (BNNs) has been a longstanding focus in computational neuroscience. A central yet unresolved challenge in BNN analysis lies in deciphering the correlations between neuronal and synaptic dynamics, their connectivity patterns, and learning process. To address this, we introduce a novel BNN analysis framework grounded in network representation learning (NRL), which leverages attention scores to uncover intricate correlations between network components and their features. Our framework integrates a new computational graph (CG)-based BNN representation, a bio-inspired graph attention network (BGAN) that enables multiscale correlation analysis across BNN representations, and an extensive BNN dataset. The CG-based representation captures key computational features, information flow, and structural relationships underlying neuronal and synaptic dynamics, while BGAN reflects the compositional structure of neurons, including dendrites, somas, and axons, as well as bidirectional information flows between BNN components. The dataset comprises publicly available models from ModelDB, reconstructed using the Python and standardized in NeuroML format, and is augmented with data derived from canonical neuron and synapse models. To our knowledge, this study is the first to apply an NRL-based approach to the full spectrum of BNNs and their analysis.
Thank you to arXiv for use of its open access interoperability. PaperDance 不是 arXiv 官方产品;中文卡片由大模型生成,请以原文为准。