arXiv:2410.12641eess.IVcs.AI2024-10被引 1

用深度学习同时分割肩骨并评估关节炎,助力手术规划。

Cascade learning in multi-task encoder-decoder networks for concurrent bone segmentation and glenohumeral joint assessment in shoulder CT scans

  • 分两阶段处理:先分割骨骼,再分类三种关节炎病变
  • 三维重建误差低于0.25mm,病灶识别准确率超90%
  • 15秒内完成全流程,适合临床使用

骨关节炎是影响骨骼和软骨的退行性疾病,常导致骨赘形成、骨密度下降及关节间隙狭窄。治疗方式依病情严重程度而异。本文提出一种新型深度学习框架,用于处理肩部CT扫描,可实现近端肱骨与肩胛骨的语义分割、三维骨表面重建、肩盂关节区域识别,并对三种常见骨关节炎相关病变进行分期:骨赘形成(OS)、关节间隙缩小(JS)及肱肩对位异常(HSA)。该流程包含两个级联的3D CNN架构:3D CEL-UNet用于分割,3D Arthro-Net用于三分类。基于包含571例患者数据的回顾性数据集进行训练、验证与测试。三维重建的均方根误差与豪斯多夫距离中位数分别为:肱骨0.22mm、1.48mm;肩胛骨0.24mm、1.48mm,优于现有方法,具备用于基于患者模型的肩关节置换术术前规划潜力。对OS、JS、HSA的分类准确率均稳定在约90%。推理时间小于15秒,展现高效性与在骨科放射科实践中的兼容性。结果表明该框架有望推动人工智能在医学中的实际应用,优化术前规划流程,提供高质量骨表面模型,支持医生根据患者个体化关节状况选择最佳手术方案。

原文摘要 · Abstract (English)

Osteoarthritis is a degenerative condition affecting bones and cartilage, often leading to osteophyte formation, bone density loss, and joint space narrowing. Treatment options to restore normal joint function vary depending on the severity of the condition. This work introduces an innovative deep-learning framework processing shoulder CT scans. It features the semantic segmentation of the proximal humerus and scapula, the 3D reconstruction of bone surfaces, the identification of the glenohumeral (GH) joint region, and the staging of three common osteoarthritic-related pathologies: osteophyte formation (OS), GH space reduction (JS), and humeroscapular alignment (HSA). The pipeline comprises two cascaded CNN architectures: 3D CEL-UNet for segmentation and 3D Arthro-Net for threefold classification. A retrospective dataset of 571 CT scans featuring patients with various degrees of GH osteoarthritic-related pathologies was used to train, validate, and test the pipeline. Root mean squared error and Hausdorff distance median values for 3D reconstruction were 0.22mm and 1.48mm for the humerus and 0.24mm and 1.48mm for the scapula, outperforming state-of-the-art architectures and making it potentially suitable for a PSI-based shoulder arthroplasty preoperative plan context. The classification accuracy for OS, JS, and HSA consistently reached around 90% across all three categories. The computational time for the inference pipeline was less than 15s, showcasing the framework's efficiency and compatibility with orthopedic radiology practice. The outcomes represent a promising advancement toward the medical translation of artificial intelligence tools. This progress aims to streamline the preoperative planning pipeline delivering high-quality bone surfaces and supporting surgeons in selecting the most suitable surgical approach according to the unique patient joint conditions.

医学影像多任务学习三维重建关节炎评估

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