arXiv:2410.18161eess.IVcs.CV2024-10被引 2

用计算机视觉自动计算脂肪比,辅助区分肠结核与克罗恩病。

Bridging the Diagnostic Divide: Classical Computer Vision and Advanced AI methods for distinguishing ITB and CD through CTE Scans

  • 提出2D图像算法自动分割皮下脂肪,计算脂肪比。
  • 深度学习模型准确率75%,但小样本下评分系统更可信。
  • 结合Grad-CAM提升模型可解释性,增强临床信任度。

肠结核(ITB)与克罗恩病(CD)因症状、临床表现和影像特征相似,诊断困难。本研究利用计算机断层扫描小肠造影(CTE)数据,结合深度学习与传统计算机视觉方法解决该问题。放射科专家共识认为内脏脂肪与皮下脂肪比(VF/SF)是区分二者的重要生物标志物。本文提出一种新型2D图像计算机视觉算法,实现皮下脂肪的自动分割,以自动化计算该比值,提升诊断效率与客观性。作为基准,将结果与TotalSegmentator深度学习工具及放射科医生手动测量进行对比,并通过切片法在3D CT数据上验证。此外,提出一种评分系统,整合脂肪比与肺结核概率等影像学特征生成综合诊断分。基于包含100例患者的样本集训练了ResNet10模型,准确率达75%。为提升可解释性,引入Grad-CAM技术解释模型预测。由于数据量较小,特征评分系统被放射科医生视为比深度学习模型更可靠的方法。

原文摘要 · Abstract (English)

Differentiating between Intestinal Tuberculosis (ITB) and Crohn's Disease (CD) poses a significant clinical challenge due to their similar symptoms, clinical presentations, and imaging features. This study leverages Computed Tomography Enterography (CTE) scans, deep learning, and traditional computer vision to address this diagnostic dilemma. A consensus among radiologists from renowned institutions has recognized the visceral-to-subcutaneous fat (VF/SF) ratio as a surrogate biomarker for differentiating between ITB and CD. Previously done manually, we propose a novel 2D image computer vision algorithm for auto-segmenting subcutaneous fat to automate this ratio calculation, enhancing diagnostic efficiency and objectivity. As a benchmark, we compare the results to those obtained using the TotalSegmentator tool, a popular deep learning-based software for automatic segmentation of anatomical structures, and manual calculations by radiologists. We also demonstrated the performance on 3D CT volumes using a slicing method and provided a benchmark comparison of the algorithm with the TotalSegmentator tool. Additionally, we propose a scoring approach to integrate scores from radiological features, such as the fat ratio and pulmonary TB probability, into a single score for diagnosis. We trained a ResNet10 model on a dataset of CTE scans with samples from ITB, CD, and normal patients, achieving an accuracy of 75%. To enhance interpretability and gain clinical trust, we integrated the explainable AI technique Grad-CAM with ResNet10 to explain the model's predictions. Due to the small dataset size (100 total cases), the feature-based scoring system is considered more reliable and trusted by radiologists compared to the deep learning model for disease diagnosis.

医学影像计算机视觉深度学习可解释性

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