arXiv:2410.20154cs.CV2024-10被引 16

用分类结果引导分割,提升肺结节边界精度。

Detection-Guided Deep Learning-Based Model with Spatial Regularization for Lung Nodule Segmentation

  • 融合分割与分类,用分类结果作为先验优化分割。
  • 在有限数据下实现0.885敏感度与0.814 Dice分数。
  • 适合医学影像分析、肺结节智能诊断研究者。

肺癌是全球癌症诊断和死亡的首要原因。早期发现肺结节对改善患者预后至关重要,而结节分割有助于医生区分良恶性病变。然而,由于结节形状大小差异大且常邻近肺组织,分割难度高。本文提出一种新型深度学习模型,整合分割与分类任务,通过特征组合模块实现两模块间信息共享。利用分类结果作为先验,结合空间正则化技术优化结节尺寸估计。针对训练数据有限问题,设计了最优迁移学习策略,冻结部分层以提升性能。实验表明,该模型比常用方法更准确捕捉目标结节;采用迁移学习后,敏感度达0.885,Dice分数为0.814。

原文摘要 · Abstract (English)

Lung cancer ranks as one of the leading causes of cancer diagnosis and is the foremost cause of cancer-related mortality worldwide. The early detection of lung nodules plays a pivotal role in improving outcomes for patients, as it enables timely and effective treatment interventions. The segmentation of lung nodules plays a critical role in aiding physicians in distinguishing between malignant and benign lesions. However, this task remains challenging due to the substantial variation in the shapes and sizes of lung nodules, and their frequent proximity to lung tissues, which complicates clear delineation. In this study, we introduce a novel model for segmenting lung nodules in computed tomography (CT) images, leveraging a deep learning framework that integrates segmentation and classification processes. This model is distinguished by its use of feature combination blocks, which facilitate the sharing of information between the segmentation and classification components. Additionally, we employ the classification outcomes as priors to refine the size estimation of the predicted nodules, integrating these with a spatial regularization technique to enhance precision. Furthermore, recognizing the challenges posed by limited training datasets, we have developed an optimal transfer learning strategy that freezes certain layers to further improve performance. The results show that our proposed model can capture the target nodules more accurately compared to other commonly used models. By applying transfer learning, the performance can be further improved, achieving a sensitivity score of 0.885 and a Dice score of 0.814.

肺结节分割深度学习医学影像

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