用视频和生理信号实时监测驾驶状态，提升自动驾驶安全性。

Road safety remains a critical challenge worldwide, with approximately 1.35 million fatalities annually attributed to traffic accidents, often due to human errors. As we advance towards higher levels of vehicle automation, challenges still exist, as driving with automation can cognitively over-demand drivers if they engage in non-driving-related tasks (NDRTs), or lead to drowsiness if driving was the sole task. This calls for the urgent need for an effective Driver Monitoring System (DMS) that can evaluate cognitive load and drowsiness in SAE Level-2/3 autonomous driving contexts. In this study, we propose a novel multi-task DMS, termed VDMoE, which leverages RGB video input to monitor driver states non-invasively. By utilizing key facial features to minimize computational load and integrating remote Photoplethysmography (rPPG) for physiological insights, our approach enhances detection accuracy while maintaining efficiency. Additionally, we optimize the Mixture-of-Experts (MoE) framework to accommodate multi-modal inputs and improve performance across different tasks. A novel prior-inclusive regularization method is introduced to align model outputs with statistical priors, thus accelerating convergence and mitigating overfitting risks. We validate our method with the creation of a new dataset (MCDD), which comprises RGB video and physiological indicators from 42 participants, and two public datasets. Our findings demonstrate the effectiveness of VDMoE in monitoring driver states, contributing to safer autonomous driving systems. The code and data will be released.