基于专家策略的深度学习模型,提升儿童脑肿瘤分割精度。
A New Logic For Pediatric Brain Tumor Segmentation
- 模仿放射科医生策略设计分割网络,区分四类肿瘤区域。
- 在30例外部数据上达Dice 0.642、HD95 73.0mm,优于现有最优模型。
- 跨数据集泛化性强,适用于儿童与成人脑瘤研究者参考。
本文提出一种新型深度学习方法,用于儿童脑肿瘤分割,灵感源自放射科专家的标注策略。模型可区分四类肿瘤区域,并在公开的PED BraTS 2024测试集上进行基准评估。此外,我们在来自CBTN(Children's Brain Tumor Network)的30例患者外部数据集上验证模型性能,标签遵循PED BraTS 2024标准,同时对比了2023年BraTS成人胶质瘤数据集的结果。与PED BraTS 2023挑战赛优胜算法相比,本模型在CBTN测试集上取得0.642的平均Dice分数和73.0 mm的HD95值,优于对比模型的0.626和84.0 mm。模型在成人胶质瘤数据集上整体肿瘤分割也达到0.877 Dice分数,超越当前SOTA。结果表明,该模型有助于更准确地评估治疗反应与病情监测。代码已开源:https://github.com/NUBagciLab/Pediatric-Brain-Tumor-Segmentation-Model。
原文摘要 · Abstract (English)
In this paper, we present a novel approach for segmenting pediatric brain tumors using a deep learning architecture, inspired by expert radiologists' segmentation strategies. Our model delineates four distinct tumor labels and is benchmarked on a held-out PED BraTS 2024 test set (i.e., pediatric brain tumor datasets introduced by BraTS). Furthermore, we evaluate our model's performance against the state-of-the-art (SOTA) model using a new external dataset of 30 patients from CBTN (Children's Brain Tumor Network), labeled in accordance with the PED BraTS 2024 guidelines and 2023 BraTS Adult Glioma dataset. We compare segmentation outcomes with the winning algorithm from the PED BraTS 2023 challenge as the SOTA model. Our proposed algorithm achieved an average Dice score of 0.642 and an HD95 of 73.0 mm on the CBTN test data, outperforming the SOTA model, which achieved a Dice score of 0.626 and an HD95 of 84.0 mm. Moreover, our model exhibits strong generalizability, attaining a 0.877 Dice score in whole tumor segmentation on the BraTS 2023 Adult Glioma dataset, surpassing existing SOTA. Our results indicate that the proposed model is a step towards providing more accurate segmentation for pediatric brain tumors, which is essential for evaluating therapy response and monitoring patient progress. Our source code is available at https://github.com/NUBagciLab/Pediatric-Brain-Tumor-Segmentation-Model.
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