提出可适配多种扫描参数的心脏MRI重建基础模型,提升图像质量并减少多模型需求。
On the Foundation Model for Cardiac MRI Reconstruction
- 通过自适应迭代步数和通道偏移优化重建过程
- 在多种加速率与对比度组合下显著提升图像质量
- 适用于临床多变扫描参数,适合医学影像研究者使用
近年来,基于机器学习的重建方法被广泛研究并应用于心脏磁共振(CMR)成像。这类方法可在大幅加速扫描条件下提供临床可接受的图像质量。然而,其训练需大量数据与计算时间,且通常针对固定加速率或图像对比度进行优化。实际中成像参数常根据诊断需求调整,可能与训练数据不一致,导致图像质量下降,需多个独立训练网络满足临床需求。本研究提出一种基础模型,结合自适应展开、通道偏移及模式与对比度提示的UNet(PCP-UNet),解决该问题。具体而言,不同加速率的欠采样数据采用不同的展开迭代次数;通道偏移提升重建质量;PCP-UNet引入图像对比度与采样模式提示。在体内CMR实验中,测试了多种对比度、加速率及采样模式的混合组合。结果表明,所提基础模型在广泛CMR协议下显著提升图像质量,优于传统基于ML的方法。
原文摘要 · Abstract (English)
In recent years, machine learning (ML) based reconstruction has been widely investigated and employed in cardiac magnetic resonance (CMR) imaging. ML-based reconstructions can deliver clinically acceptable image quality under substantially accelerated scans. ML-based reconstruction, however, also requires substantial data and computational time to train the neural network, which is often optimized for a fixed acceleration rate or image contrast. In practice, imaging parameters are often tuned to best suit the diagnosis, which may differ from the training data. This can result in degraded image quality, and multiple trained networks are needed to fulfill the clinical demands. In this study, we propose a foundation model that uses adaptive unrolling, channel-shifting, and Pattern and Contrast-Prompt-UNet (PCP-UNet) to tackle the problem. In particular, the undersampled data goes through a different number of unrolled iterations according to its acceleration rate. Channel-shifting improves reconstructed data quality. The PCP-UNet is equipped with an image contrast and sampling pattern prompt. In vivo CMR experiments were performed using mixed combinations of image contrasts, acceleration rates, and (under)sampling patterns. The proposed foundation model has significantly improved image quality for a wide range of CMR protocols and outperforms the conventional ML-based method.
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