针对超声心动图分割中伪标签质量差的问题,提出误差反思机制提升半监督效果。
A Semi-Supervised Approach with Error Reflection for Echocardiography Segmentation
- 通过重建反射与引导修正两阶段策略,让模型自我修正分割错误。
- 在4个公开数据集上达到90.1%~92.7%的Dice分数,优于现有方法。
- 适合医疗图像分割、尤其超声心动图标注稀缺场景的研究者使用。
从超声心动图中分割内部结构对心脏病的诊断与治疗至关重要。半监督学习能缓解标注数据稀缺问题。尽管现有半监督方法在多种医学影像分割中表现良好,但很少针对超声心动图特有的低对比度、模糊边缘和噪声等问题设计专门方法。这些问题影响基于Mean Teacher的高质量伪标签生成。受人类反思错误行为的启发,本文提出一种用于超声心动图半监督分割的误差反射策略。该过程使模型反思未标记图像分割中的不准确之处,从而增强伪标签的鲁棒性。具体分为两步:第一是重建反射,网络需从未标记图像的语义掩码及其辅助草图重建真实代理图像,并最大化原始输入与代理图像间的结构相似性;第二是引导修正,通过重建误差图解耦不可靠分割区域,利用高密度区域附近更可靠的样本指导潜在位于决策边界附近的不可靠数据优化。此外,引入多尺度混合增强策略,缩小有标签与无标签图像之间的经验分布差距,感知心脏解剖结构的多样尺度。大量实验表明,所提方法具有竞争力。
原文摘要 · Abstract (English)
Segmenting internal structure from echocardiography is essential for the diagnosis and treatment of various heart diseases. Semi-supervised learning shows its ability in alleviating annotations scarcity. While existing semi-supervised methods have been successful in image segmentation across various medical imaging modalities, few have attempted to design methods specifically addressing the challenges posed by the poor contrast, blurred edge details and noise of echocardiography. These characteristics pose challenges to the generation of high-quality pseudo-labels in semi-supervised segmentation based on Mean Teacher. Inspired by human reflection on erroneous practices, we devise an error reflection strategy for echocardiography semi-supervised segmentation architecture. The process triggers the model to reflect on inaccuracies in unlabeled image segmentation, thereby enhancing the robustness of pseudo-label generation. Specifically, the strategy is divided into two steps. The first step is called reconstruction reflection. The network is tasked with reconstructing authentic proxy images from the semantic masks of unlabeled images and their auxiliary sketches, while maximizing the structural similarity between the original inputs and the proxies. The second step is called guidance correction. Reconstruction error maps decouple unreliable segmentation regions. Then, reliable data that are more likely to occur near high-density areas are leveraged to guide the optimization of unreliable data potentially located around decision boundaries. Additionally, we introduce an effective data augmentation strategy, termed as multi-scale mixing up strategy, to minimize the empirical distribution gap between labeled and unlabeled images and perceive diverse scales of cardiac anatomical structures. Extensive experiments demonstrate the competitiveness of the proposed method.
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