用自监督学习分析肠镜图像,自动诊断溃疡性结肠炎并评估严重程度。
Diagnosis and Severity Assessment of Ulcerative Colitis using Self Supervised Learning
- 采用自监督学习框架,无需大量标注数据即可训练模型。
- 在LIMUC数据集上,自监督模型比监督学习模型表现更优。
- 适合医疗资源不足地区,降低专家标注依赖,加速诊疗流程。
溃疡性结肠炎(UC)是一种无法治愈的炎症性肠病,可导致大肠和直肠出现溃疡。随着发病率上升及胃肠科医生短缺,医疗系统压力增大,患者诊疗受限。目前通过肠镜检查诊断UC并依据梅奥内镜评分(MES)评估病情严重程度,评分范围为0到3,0表示无炎症,3表示炎症显著。人工智能(AI)中的卷积神经网络(CNN)可将肠镜分析视为多分类问题,实现对UC的诊断与严重程度判断。以往研究依赖监督学习,需大规模标注数据,但标注过程耗时费力且成本高昂。为此,本研究采用自监督学习(SSL)框架,在未标注数据上高效训练,以分析肠镜图像并辅助诊断。与监督学习模型相比,基于SwAV和SparK的自监督框架在目前最大的公开肠镜图像数据集LIMUC上表现更优。
原文摘要 · Abstract (English)
Ulcerative Colitis (UC) is an incurable inflammatory bowel disease that leads to ulcers along the large intestine and rectum. The increase in the prevalence of UC coupled with gastrointestinal physician shortages stresses the healthcare system and limits the care UC patients receive. A colonoscopy is performed to diagnose UC and assess its severity based on the Mayo Endoscopic Score (MES). The MES ranges between zero and three, wherein zero indicates no inflammation and three indicates that the inflammation is markedly high. Artificial Intelligence (AI)-based neural network models, such as convolutional neural networks (CNNs) are capable of analyzing colonoscopies to diagnose and determine the severity of UC by modeling colonoscopy analysis as a multi-class classification problem. Prior research for AI-based UC diagnosis relies on supervised learning approaches that require large annotated datasets to train the CNNs. However, creating such datasets necessitates that domain experts invest a significant amount of time, rendering the process expensive and challenging. To address the challenge, this research employs self-supervised learning (SSL) frameworks that can efficiently train on unannotated datasets to analyze colonoscopies and, aid in diagnosing UC and its severity. A comparative analysis with supervised learning models shows that SSL frameworks, such as SwAV and SparK outperform supervised learning models on the LIMUC dataset, the largest publicly available annotated dataset of colonoscopy images for UC.
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