直接处理不规则临床时间序列,兼顾时序与传感器间关系建模。
WaveGNN: Integrating Graph Neural Networks and Transformers for Decay-Aware Classification of Irregular Clinical Time-Series
- 用衰减感知Transformer捕捉单个序列内部动态变化
- 为每条数据生成稀疏可解释的样本专属图,建模跨传感器长期与短期关系
- 在多个真实数据集上表现稳定,适合临床决策支持场景
临床时间序列常因采样不规则、传感器频率差异、数据缺失及时间戳错位而难以处理。以往方法通常通过插值转换为规则序列,引入偏差;或生成不一致且不可解释的传感器关系,影响对序列内与序列间依赖的准确学习。本文提出WaveGNN,直接作用于不规则多变量时间序列,无需插值或转为规则表示。模型结合衰减感知Transformer捕捉序列内动态,以及样本特定的图神经网络,建模短时与长时跨传感器关系,从而为每个样本生成单一、稀疏且可解释的图结构。在P12、P19、MIMIC-III和PAM等多个基准数据集上,WaveGNN表现出持续优异性能,优于多数先进基线方法。尽管并非在所有任务中均胜出,但其在多样化场景下的稳健性尤为突出。此外,学习到的图结构与已知生理结构高度吻合,提升模型可解释性,支持临床决策。
原文摘要 · Abstract (English)
Clinical time series are often irregularly sampled, with varying sensor frequencies, missing observations, and misaligned timestamps. Prior approaches typically address these irregularities by interpolating data into regular sequences, thereby introducing bias, or by generating inconsistent and uninterpretable relationships across sensor measurements, complicating the accurate learning of both intra-series and inter-series dependencies. We introduce WaveGNN, a model that operates directly on irregular multivariate time series without interpolation or conversion to a regular representation. WaveGNN combines a decay-aware Transformer to capture intra-series dynamics with a sample-specific graph neural network that models both short-term and long-term inter-sensor relationships. Therefore, it generates a single, sparse, and interpretable graph per sample. Across multiple benchmark datasets (P12, P19, MIMIC-III, and PAM), WaveGNN delivers consistently strong performance, whereas other state-of-the-art baselines tend to perform well on some datasets or tasks but poorly on others. While WaveGNN does not necessarily surpass every method in every case, its consistency and robustness across diverse settings set it apart. Moreover, the learned graphs align well with known physiological structures, enhancing interpretability and supporting clinical decision-making.
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