arXiv:2412.10985eess.IVcs.CV2024-12被引 1

用CT数据训练的网络,从模糊CMR图像重建心脏精细结构。

MorphiNet: A Graph Subdivision Network for Adaptive Bi-ventricle Surface Reconstruction

  • 通过梯度场变形模板网格,实现自适应心室表面重建
  • 在法洛氏四联症患者上达0.3更高Dice分数,2.6更低豪斯多夫距离
  • 速度快50倍,适合临床实时分析,尤其适合心脏功能评估

心脏磁共振(CMR)成像因能清晰显示软组织和动态功能,被广泛用于心脏模型重建与数字孪生计算分析。然而,其各向异性特征导致层间间距大且受心脏运动影响易错位,造成数据丢失与测量误差,难以捕捉精细解剖结构。本文提出MorphiNet,一种从高分辨率计算机断层扫描(CT)图像中学习心腔解剖先验、无需与CMR配对的新网络。该方法将解剖结构编码为梯度场,通过多层图细分网络将模板网格变形为个体化几何形态,同时保持密集点对应关系,适用于计算分析。MorphiNet在法洛氏四联症患者上达到0.3更高的Dice分数与2.6更低的豪斯多夫距离,优于现有最优模板方法;在保持神经隐式函数方法解剖精度的同时,推理速度提升50倍。跨数据集验证(自动化心脏诊断挑战赛)表明其泛化能力,达到0.7的Dice分数,比以往模板方法提升30%。通过成功恢复缺失心脏结构,验证了其解剖学习的有效性,并显著优于标准环细分法。运动追踪实验进一步证明其可用于心脏功能分析,可准确计算射血分数并识别法洛氏四联症患者的肌功能障碍。

原文摘要 · Abstract (English)

Cardiac Magnetic Resonance (CMR) imaging is widely used for heart model reconstruction and digital twin computational analysis because of its ability to visualize soft tissues and capture dynamic functions. However, CMR images have an anisotropic nature, characterized by large inter-slice distances and misalignments from cardiac motion. These limitations result in data loss and measurement inaccuracies, hindering the capture of detailed anatomical structures. In this work, we introduce MorphiNet, a novel network that reproduces heart anatomy learned from high-resolution Computed Tomography (CT) images, unpaired with CMR images. MorphiNet encodes the anatomical structure as gradient fields, deforming template meshes into patient-specific geometries. A multilayer graph subdivision network refines these geometries while maintaining a dense point correspondence, suitable for computational analysis. MorphiNet achieved state-of-the-art bi-ventricular myocardium reconstruction on CMR patients with tetralogy of Fallot with 0.3 higher Dice score and 2.6 lower Hausdorff distance compared to the best existing template-based methods. While matching the anatomical fidelity of comparable neural implicit function methods, MorphiNet delivered 50$\times$ faster inference. Cross-dataset validation on the Automated Cardiac Diagnosis Challenge confirmed robust generalization, achieving a 0.7 Dice score with 30\% improvement over previous template-based approaches. We validate our anatomical learning approach through the successful restoration of missing cardiac structures and demonstrate significant improvement over standard Loop subdivision. Motion tracking experiments further confirm MorphiNet's capability for cardiac function analysis, including accurate ejection fraction calculation that correctly identifies myocardial dysfunction in tetralogy of Fallot patients.

心脏建模图像重建图神经网络医学影像

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