arXiv:2412.11377eess.IVcs.AI2024-12被引 1

用新激活函数提升胎儿脑部测量精度,减少人工误差。

Improving Automatic Fetal Biometry Measurement with Swoosh Activation Function

  • 提出Swoosh激活函数,优化热图预测的聚焦性
  • FTD相关性提升,FHC测量误差降低
  • 适配多种模型,可灵活调整参数

胎儿丘脑直径(FTD)和头围(FHC)测量对早期发现神经发育异常至关重要。但2D超声图像手动测量耗时、易受观察者差异影响,且图像信噪比低。现有最先进方法BiometryNet在测量这两项指标时表现不足,因其无法处理结构模糊边缘及复杂形状。为此,本文提出新型Swoosh激活函数(SAF),作为热图生成的正则化项,使预测热图的均方误差(MSE)更接近最优水平,减少热点分散。实验表明,SAF在FTD测量中显著提高组内相关系数,在FHC测量中降低平均偏差,优于当前最先进算法BiometryNet。该方法具有高度泛化性和架构无关性,系数可针对不同任务调节,具备强可定制性。本研究证明SAF能有效提升胎儿生物测量中的关键点检测精度,有望改善胎儿监测与新生儿预后。

原文摘要 · Abstract (English)

The measurement of fetal thalamus diameter (FTD) and fetal head circumference (FHC) are crucial in identifying abnormal fetal thalamus development as it may lead to certain neuropsychiatric disorders in later life. However, manual measurements from 2D-US images are laborious, prone to high inter-observer variability, and complicated by the high signal-to-noise ratio nature of the images. Deep learning-based landmark detection approaches have shown promise in measuring biometrics from US images, but the current state-of-the-art (SOTA) algorithm, BiometryNet, is inadequate for FTD and FHC measurement due to its inability to account for the fuzzy edges of these structures and the complex shape of the FTD structure. To address these inadequacies, we propose a novel Swoosh Activation Function (SAF) designed to enhance the regularization of heatmaps produced by landmark detection algorithms. Our SAF serves as a regularization term to enforce an optimum mean squared error (MSE) level between predicted heatmaps, reducing the dispersiveness of hotspots in predicted heatmaps. Our experimental results demonstrate that SAF significantly improves the measurement performances of FTD and FHC with higher intraclass correlation coefficient scores in FTD and lower mean difference scores in FHC measurement than those of the current SOTA algorithm BiometryNet. Moreover, our proposed SAF is highly generalizable and architecture-agnostic. The SAF's coefficients can be configured for different tasks, making it highly customizable. Our study demonstrates that the SAF activation function is a novel method that can improve measurement accuracy in fetal biometry landmark detection. This improvement has the potential to contribute to better fetal monitoring and improved neonatal outcomes.

医学影像超声深度学习热图优化

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