arXiv:2412.11681eess.IVcs.AI2024-12被引 4

用深度学习模型自动识别胸片中的肺病和肺癌结节,准确率超77%。

Fast-staged CNN Model for Accurate pulmonary diseases and Lung cancer detection

  • 分两阶段筛查:先判正常异常,再识别具体病灶
  • 外部验证中结节检测准确率达77%,AUC为0.888
  • 适用于基层医疗辅助诊断,尤其缺放射科医生的地区

肺部疾病是全球重大健康问题,若未能及时诊断治疗常导致死亡。胸部放射摄影是主要诊断手段,但经验丰富的放射科医生资源有限。人工智能与计算机视觉的发展为此提供新方案。本研究评估了一种深度学习模型,利用超过13.5万张正位胸片,检测肺结节及八种其他肺部病变。采用基于集成方法与迁移学习的两阶段分类系统:首先将图像分为正常或异常,再识别具体病理类型。模型在外部验证中表现良好,结节分类准确率为77%,敏感度0.713,特异度0.776,AUC达0.888。尽管存在部分误判(多为假阴性),模型仍展现出跨人群的良好泛化能力,归因于训练数据的地理多样性。未来可结合ETL数据分布策略并扩充结节样本以提升精度。

原文摘要 · Abstract (English)

Pulmonary pathologies are a significant global health concern, often leading to fatal outcomes if not diagnosed and treated promptly. Chest radiography serves as a primary diagnostic tool, but the availability of experienced radiologists remains limited. Advances in Artificial Intelligence (AI) and machine learning, particularly in computer vision, offer promising solutions to address this challenge. This research evaluates a deep learning model designed to detect lung cancer, specifically pulmonary nodules, along with eight other lung pathologies, using chest radiographs. The study leverages diverse datasets comprising over 135,120 frontal chest radiographs to train a Convolutional Neural Network (CNN). A two-stage classification system, utilizing ensemble methods and transfer learning, is employed to first triage images into Normal or Abnormal categories and then identify specific pathologies, including lung nodules. The deep learning model achieves notable results in nodule classification, with a top-performing accuracy of 77%, a sensitivity of 0.713, a specificity of 0.776 during external validation, and an AUC score of 0.888. Despite these successes, some misclassifications were observed, primarily false negatives. In conclusion, the model demonstrates robust potential for generalization across diverse patient populations, attributed to the geographic diversity of the training dataset. Future work could focus on integrating ETL data distribution strategies and expanding the dataset with additional nodule-type samples to further enhance diagnostic accuracy.

肺结节检测深度学习医学影像胸片分析

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