用微球追踪法测量微泳者在复杂流场中的运动，突破环境干扰难题。
Measuring DNA Microswimmer Locomotion in Complex Flow Environments
- 用磁性和非磁性微球追踪流场，分离自驱动与环境扰动
- 定量测出微泳者相对流体的磁场驱动位移
- 适用于动态流场中微机器人导航研究
微泳者是亚毫米级游泳微型机器人，在靶向药物递送和微创手术等应用中具有潜力。要实现这些目标，微泳者需能在动态流体环境和力场中自主导航。然而，由于难以区分微泳者自身运动与环境引起的运动，相关实验研究仍十分有限。本文提出一种基于示踪微球的方法，通过跟踪铁磁性和非磁性聚苯乙烯示踪微球的运动，捕捉流体流动和场梯度对微泳者轨迹的影响。进而计算出微泳者相对于流体的磁场驱动位移，并通过多个微泳者在不同流场中的运动演示了该方法的有效性。
原文摘要 · Abstract (English)
Microswimmers are sub-millimeter swimming microrobots that show potential as a platform for controllable locomotion in applications including targeted cargo delivery and minimally invasive surgery. To be viable for these target applications, microswimmers will eventually need to be able to navigate in environments with dynamic fluid flows and forces. Experimental studies with microswimmers towards this goal are currently rare because of the difficulty isolating intentional microswimmer motion from environment-induced motion. In this work, we present a method for measuring microswimmer locomotion within a complex flow environment using fiducial microspheres. By tracking the particle motion of ferromagnetic and non-magnetic polystyrene fiducial microspheres, we capture the effect of fluid flow and field gradients on microswimmer trajectories. We then determine the field-driven translation of these microswimmers relative to fluid flow and demonstrate the effectiveness of this method by illustrating the motion of multiple microswimmers through different flows.
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