用个性化提示让大模型更懂病人,提升医疗建议精准度
Learning Personalized Prompts for Healthcare Guidance
- 基于患者自身与相似病例数据生成定制提示
- 强化学习优化提示,使回答匹配医生建议
- 在产科真实数据上专家评测胜率97%
大型语言模型的快速发展已深刻影响医疗领域。现实中,医院和患者亟需能理解个人健康记录并提供个性化医疗建议的系统。然而现有方法主要依赖通用医学知识,难以考虑个体差异,导致建议泛化。为此,我们提出个性化提示学习(PPL)框架,通过融合患者自述信息与临床相似病例的共性信号,构建初始个性化提示,并利用强化学习进一步优化,使模型输出更贴合每位患者的医生建议。PPL采用硬提示机制,可无缝集成至私有大模型而无需修改底层结构。我们在真实产科妇科数据上评估该方法,结果表明其生成的医疗建议更具个性化,在专家评测中100次对比中胜出97次,展现出广泛医疗应用潜力。代码已开源:https://github.com/CGCL-codes/PPL。
原文摘要 · Abstract (English)
The rapid development of large language models (LLMs) has transformed many industries, including healthcare. In practice, hospitals and patients increasingly seek LLM-based systems capable of interpreting personal health records and providing healthcare guidance. However, existing approaches mainly rely on general medical knowledge and often fail to account for individual variability, limiting their ability to provide personalized guidance. To address this, we propose personalized prompt learning (PPL), a framework that learns individualized prompts to guide LLMs in generating personalized healthcare recommendations. PPL constructs initial personalized prompts by leveraging both self-informed patient information and peer-informed signals derived from clinically similar cases. These prompts are then refined using reinforcement learning (RL) to better align the generated responses with physician recommendations written for each patient. PPL operates with hard prompts, enabling seamless integration with proprietary LLMs without modifying the underlying models. We evaluate PPL on real-world obstetrics and gynecology data. The results show that our approach produces more personalized healthcare guidance and wins 97 out of 100 comparisons in expert evaluation, demonstrating its potential for broader healthcare applications. Our code is publicly available at https://github.com/CGCL-codes/PPL.
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