构建四类病原体专用术语体系，提升传染病数据整合效率。
A Fourfold Pathogen Reference Ontology Suite
- 以中心-分支架构扩展传染病本体，生成病毒、细菌等四类专有术语集。
- 形成可复用的模块化结构，支持跨病原体数据整合与共享。
- 适用于生物医学数据标准化、流行病研究及智能分析系统开发。
传染病仍是全球重大健康挑战，标准化本体在数据管理中至关重要。现有传染病本体（IDO）及其扩展（如冠状病毒传染病本体CIDO）对信息组织与传播具有关键作用。新冠疫情凸显了更新IDO及其病毒特异性扩展的紧迫性，同时亟需更新针对细菌、真菌和寄生虫感染的扩展。本文采用“中心-分支”方法，构建了病毒性传染病本体（VIDO）、细菌性传染病本体（BIDO）、真菌性感染本体（MIDO）和寄生虫性传染病本体（PIDO）。这些病原体特异性参考本体提升了IDO生态系统内传染病数据的模块化与可复用性。未来工作将聚焦于进一步优化这些本体、拓展新扩展，并基于其开发应用本体，持续推动生物医学术语标准化，以促进数据共享与分析。
原文摘要 · Abstract (English)
Infectious diseases remain a critical global health challenge, and the integration of standardized ontologies plays a vital role in managing related data. The Infectious Disease Ontology (IDO) and its extensions, such as the Coronavirus Infectious Disease Ontology (CIDO), are essential for organizing and disseminating information related to infectious diseases. The COVID-19 pandemic highlighted the need for updating IDO and its virus-specific extensions. There is an additional need to update IDO extensions specific to bacteria, fungus, and parasite infectious diseases. We adopt the "hub and spoke" methodology to generate pathogen-specific extensions of IDO: Virus Infectious Disease Ontology (VIDO), Bacteria Infectious Disease Ontology (BIDO), Mycosis Infectious Disease Ontology (MIDO), and Parasite Infectious Disease Ontology (PIDO). The creation of pathogen-specific reference ontologies advances modularization and reusability of infectious disease data within the IDO ecosystem. Future work will focus on further refining these ontologies, creating new extensions, and developing application ontologies based on them, in line with ongoing efforts to standardize biological and biomedical terminologies for improved data sharing and analysis.
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