arXiv:2501.04140physics.med-pheess.IV2025-01被引 6

用时空高斯表示法,从少角度投影重建高质量4D放疗影像。

Spatiotemporal Gaussian Optimization for 4D Cone Beam CT Reconstruction from Sparse Projections

  • 用可学习的时空高斯点云建模动态物体,实现高效重建
  • 在1分钟内完成重建,大幅减少扫描时间和辐射剂量
  • 适合需要低剂量、高精度呼吸运动捕捉的放疗场景

在图像引导放疗中,四维锥形束计算机断层扫描(4D-CBCT)对评估患者呼吸周期中的肿瘤运动至关重要。然而,生成高质量4D-CBCT需远多于标准3D-CBCT的投影数,导致扫描时间延长和患者辐射剂量增加。为应对这一挑战,亟需一种能从1分钟内的3D-CBCT采集数据重建高质量4D-CBCT的方法。核心难点在于投影稀疏采样带来的严重条纹伪影,影响图像质量。本文提出一种新框架,利用时空高斯表示法从稀疏投影中重建4D-CBCT,平衡条纹抑制、运动保真与细节恢复。每个高斯具有三维位置、协方差、旋转和密度属性,通过射线光栅化生成二维投影图,并优化高斯参数以最小化实测与渲染投影间的差异。同时引入高斯变形网络,联合优化高斯属性以获得动态4D表示。最终通过体素化4D高斯生成高质量4D-CBCT图像,有效保留运动动态与空间细节。代码与结果见:https://github.com/fuyabo/4DGS_for_4DCBCT/tree/main

原文摘要 · Abstract (English)

In image-guided radiotherapy (IGRT), four-dimensional cone-beam computed tomography (4D-CBCT) is critical for assessing tumor motion during a patients breathing cycle prior to beam delivery. However, generating 4D-CBCT images with sufficient quality requires significantly more projection images than a standard 3D-CBCT scan, leading to extended scanning times and increased imaging dose to the patient. To address these limitations, there is a strong demand for methods capable of reconstructing high-quality 4D-CBCT images from a 1-minute 3D-CBCT acquisition. The challenge lies in the sparse sampling of projections, which introduces severe streaking artifacts and compromises image quality. This paper introduces a novel framework leveraging spatiotemporal Gaussian representation for 4D-CBCT reconstruction from sparse projections, achieving a balance between streak artifact reduction, dynamic motion preservation, and fine detail restoration. Each Gaussian is characterized by its 3D position, covariance, rotation, and density. Two-dimensional X-ray projection images can be rendered from the Gaussian point cloud representation via X-ray rasterization. The properties of each Gaussian were optimized by minimizing the discrepancy between the measured projections and the rendered X-ray projections. A Gaussian deformation network is jointly optimized to deform these Gaussian properties to obtain a 4D Gaussian representation for dynamic CBCT scene modeling. The final 4D-CBCT images are reconstructed by voxelizing the 4D Gaussians, achieving a high-quality representation that preserves both motion dynamics and spatial detail. The code and reconstruction results can be found at https://github.com/fuyabo/4DGS_for_4DCBCT/tree/main

4D成像放射治疗高斯表示稀疏重建

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