用TSE序列实现金属植入物附近磁场不均匀性精准测量

Purpose: To propose a B1+ mapping technique for imaging of body parts containing metal hardware, based on magnitude images acquired with turbo spin echo (TSE) pulse sequences. Theory and Methods: To encode the underlying B1+, multiple (two to four) TSE image sets with various excitation and refocusing flip angles were acquired. To this end, the acquired signal intensities were matched to a database of simulated signals which was generated by solving the Bloch equations taking into account the exact sequence parameters. The retrieved B1+ values were validated against gradient-recalled and spin echo dual angle methods, as well as a vendor-provided turboFLASH-based mapping sequence, in gel phantoms and human subjects without and with metal implants. Results: In the absence of metal, phantom experiments demonstrated excellent agreement between the proposed technique using three or four flip angle sets and reference dual angle methods. In human subjects without metal implants, the proposed technique with three or four flip angle sets showed excellent correlation with the spin echo dual angle method. In the presence of metal, both phantoms and human subjects revealed a narrow range of B1+ estimation with the reference techniques, whereas the proposed technique successfully resolved B1+ near the metal. In select cases, the technique was implemented in conjunction with multispectral metal artifact reduction sequences and successfully applied for B1+ shimming. Conclusion: The proposed technique enables resolution of B1+ values in regions near metal hardware, overcoming susceptibility-related and narrow-range limitations of standard mapping techniques.