通过帧内与跨帧拓扑一致性提升冠状动脉斑块分割精度,仅用少量标注数据达到监督模型效果。
An Intra- and Cross-frame Topological Consistency Scheme for Semi-supervised Atherosclerotic Coronary Plaque Segmentation
- 设计双任务网络同步预测分割掩码与骨骼感知距离变换,实现帧内拓扑一致性约束。
- 引入无监督像素流估计器,确保相邻帧间斑块结构的空间连续性,提升边界清晰度。
- 在两个CTA数据集上表现优于现有半监督方法,且具备良好泛化能力,适合医学图像分析研究者。
从计算机断层扫描血管造影(CTA)图像中精准分割冠状动脉粥样硬化斑块对冠状动脉粥样硬化分析(CAA)至关重要,该分析依赖于通过曲面重形成重建的血管横截面图像。由于斑块与血管边界模糊、结构复杂,现有深度学习模型性能受限,加之标注难度大,问题尤为突出。为此,我们提出一种新型双一致性半监督框架,融合帧内拓扑一致性(ITC)与跨帧拓扑一致性(CTC),有效利用有标签和无标签数据。ITC采用双任务网络同时预测分割掩码与骨骼感知距离变换(SDT),通过一致性约束实现拓扑结构相似性,无需额外标注。CTC则使用无监督估计算法分析相邻帧间骨架与边界的像素流,保障空间连续性。在两个CTA数据集上的实验表明,本方法超越现有半监督方法,接近监督学习性能。此外,在ACDC数据集上也优于其他方法,体现良好泛化能力。
原文摘要 · Abstract (English)
Enhancing the precision of segmenting coronary atherosclerotic plaques from CT Angiography (CTA) images is pivotal for advanced Coronary Atherosclerosis Analysis (CAA), which distinctively relies on the analysis of vessel cross-section images reconstructed via Curved Planar Reformation. This task presents significant challenges due to the indistinct boundaries and structures of plaques and blood vessels, leading to the inadequate performance of current deep learning models, compounded by the inherent difficulty in annotating such complex data. To address these issues, we propose a novel dual-consistency semi-supervised framework that integrates Intra-frame Topological Consistency (ITC) and Cross-frame Topological Consistency (CTC) to leverage labeled and unlabeled data. ITC employs a dual-task network for simultaneous segmentation mask and Skeleton-aware Distance Transform (SDT) prediction, achieving similar prediction of topology structure through consistency constraint without additional annotations. Meanwhile, CTC utilizes an unsupervised estimator for analyzing pixel flow between skeletons and boundaries of adjacent frames, ensuring spatial continuity. Experiments on two CTA datasets show that our method surpasses existing semi-supervised methods and approaches the performance of supervised methods on CAA. In addition, our method also performs better than other methods on the ACDC dataset, demonstrating its generalization.
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