开源大模型可高效辅助德国泌尿科肿瘤病历书写,7-120亿参数模型表现最优。
Can open source large language models be used for tumor documentation in Germany? -- An evaluation on urological doctors' notes
- 测试11个开源LLM在3项肿瘤记录任务上的表现,采用德国泌尿科医生原始病历数据。
- Llama 3.1 8B、Mistral 7B等7-120亿参数模型表现最佳,大模型无进一步增益。
- 少于70亿参数模型性能显著下降,跨领域示例提升少样本效果,适合临床部署。
德国肿瘤病历多依赖人工录入,效率低且易出错。本文评估了11个参数量从10亿到700亿不等的开源大语言模型在三项核心任务中的表现:识别肿瘤诊断、分配ICD-10编码、提取首次诊断日期。基于匿名泌尿科医生笔记构建了标注数据集,并采用多种提示策略测试少样本学习效果及模型通用能力。结果表明,Llama 3.1 8B、Mistral 7B和Mistral NeMo 12B表现优异;训练数据较少或参数少于70亿的模型性能明显下降,而更大模型未带来进一步提升。跨医学领域示例也能改善少样本效果,显示模型具备泛化潜力。70亿至120亿参数模型在性能与资源消耗间取得平衡,经微调与优化提示后有望成为临床文档自动化的重要工具。代码与数据集已开源,填补德语医学NLP真实基准空白。
原文摘要 · Abstract (English)
Tumor documentation in Germany is largely done manually, requiring reading patient records and entering data into structured databases. Large language models (LLMs) could potentially enhance this process by improving efficiency and reliability. This evaluation tests eleven different open source LLMs with sizes ranging from 1-70 billion model parameters on three basic tasks of the tumor documentation process: identifying tumor diagnoses, assigning ICD-10 codes, and extracting the date of first diagnosis. For evaluating the LLMs on these tasks, a dataset of annotated text snippets based on anonymized doctors' notes from urology was prepared. Different prompting strategies were used to investigate the effect of the number of examples in few-shot prompting and to explore the capabilities of the LLMs in general. The models Llama 3.1 8B, Mistral 7B, and Mistral NeMo 12 B performed comparably well in the tasks. Models with less extensive training data or having fewer than 7 billion parameters showed notably lower performance, while larger models did not display performance gains. Examples from a different medical domain than urology could also improve the outcome in few-shot prompting, which demonstrates the ability of LLMs to handle tasks needed for tumor documentation. Open source LLMs show a strong potential for automating tumor documentation. Models from 7-12 billion parameters could offer an optimal balance between performance and resource efficiency. With tailored fine-tuning and well-designed prompting, these models might become important tools for clinical documentation in the future. The code for the evaluation is available from https://github.com/stefan-m-lenz/UroLlmEval. We also release the dataset as a new valuable resource that addresses the shortage of authentic and easily accessible benchmarks in German-language medical NLP.
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