arXiv:2501.13135q-bio.OTcs.AI2025-01综述被引 4

AI助力显微成像,突破生命科学研究的数据瓶颈

Applications and Challenges of AI and Microscopy in Life Science Research: A Review

  • 从人工智能视角系统梳理显微成像与生物数据融合方法
  • 指出数据异构性与标注稀缺是核心挑战,提出应对思路
  • 适合跨学科研究者了解AI在生命科学中的应用前景

人类生物学的复杂性和精密系统蕴含着推动健康进步、疾病治疗和科学发现的巨大潜力。然而,传统人工研究生物相互作用的方法常受限于生物数据的海量与复杂。人工智能凭借处理大规模数据的能力,为解决这些挑战提供了变革性路径。本文探讨了人工智能与显微成像在生命科学领域的交叉应用,重点分析其潜在价值及面临挑战。系统回顾了各类生物系统如何受益于AI,并强调该领域特有的数据类型与标注需求。特别聚焦显微成像数据,讨论处理与解析所需的人工智能技术。针对数据异构性与标注稀缺等难题,提出可能解决方案与新兴趋势。本文主要从人工智能视角出发,旨在为从事人工智能、显微成像与生物学交叉研究的学者提供参考资源。总结当前进展、关键洞见与开放问题,促进理解并鼓励跨学科合作。通过全面而简洁的领域综述,期望推动创新,促进跨领域交流,加速人工智能在生命科学研究中的应用。

原文摘要 · Abstract (English)

The complexity of human biology and its intricate systems holds immense potential for advancing human health, disease treatment, and scientific discovery. However, traditional manual methods for studying biological interactions are often constrained by the sheer volume and complexity of biological data. Artificial Intelligence (AI), with its proven ability to analyze vast datasets, offers a transformative approach to addressing these challenges. This paper explores the intersection of AI and microscopy in life sciences, emphasizing their potential applications and associated challenges. We provide a detailed review of how various biological systems can benefit from AI, highlighting the types of data and labeling requirements unique to this domain. Particular attention is given to microscopy data, exploring the specific AI techniques required to process and interpret this information. By addressing challenges such as data heterogeneity and annotation scarcity, we outline potential solutions and emerging trends in the field. Written primarily from an AI perspective, this paper aims to serve as a valuable resource for researchers working at the intersection of AI, microscopy, and biology. It summarizes current advancements, key insights, and open problems, fostering an understanding that encourages interdisciplinary collaborations. By offering a comprehensive yet concise synthesis of the field, this paper aspires to catalyze innovation, promote cross-disciplinary engagement, and accelerate the adoption of AI in life science research.

人工智能显微成像生命科学跨学科

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