用2D去噪器融合实现3D医学CT低剂量重建,速度快质量高。
Sparse Measurement Medical CT Reconstruction using Multi-Fused Block Matching Denoising Priors
- 用多切片融合的2D去噪器模拟3D先验,避免训练
- 在临床数据上达到与3D先验相当的图像质量
- 适合低剂量、稀疏投影的实时医学影像重建
医学X射线CT成像中,减少射线投影数可降低辐射剂量并缩短扫描时间,但会导致欠定逆问题,需依赖表达能力强且计算可行的先验模型。传统滤波反投影(FBP)因依赖香农-奈奎斯特采样定理,在稀疏测量下易产生伪影。共识平衡(Consensus Equilibrium)作为模型基迭代重建(MBIR)的新进展,可在无优化框架下整合多个去噪器作为先验,捕捉复杂非线性信息。然而,基于插件式方法的3D先验建模因计算需求高导致处理时间长。本文提出一种无需训练的BM3D多切片融合(BM3D-MSF)先验,通过融合多个2D去噪器,模拟全3D先验效果。该方法规避了患者数据训练的伦理问题,且适用于不同噪声和测量稀疏度场景。实验表明,与完全3D先验相比,该方法在临床CT数据上实现了相当的重建质量,同时显著降低计算复杂度。
原文摘要 · Abstract (English)
A major challenge for medical X-ray CT imaging is reducing the number of X-ray projections to lower radiation dosage and reduce scan times without compromising image quality. However these under-determined inverse imaging problems rely on the formulation of an expressive prior model to constrain the solution space while remaining computationally tractable. Traditional analytical reconstruction methods like Filtered Back Projection (FBP) often fail with sparse measurements, producing artifacts due to their reliance on the Shannon-Nyquist Sampling Theorem. Consensus Equilibrium, which is a generalization of Plug and Play, is a recent advancement in Model-Based Iterative Reconstruction (MBIR), has facilitated the use of multiple denoisers are prior models in an optimization free framework to capture complex, non-linear prior information. However, 3D prior modelling in a Plug and Play approach for volumetric image reconstruction requires long processing time due to high computing requirement. Instead of directly using a 3D prior, this work proposes a BM3D Multi Slice Fusion (BM3D-MSF) prior that uses multiple 2D image denoisers fused to act as a fully 3D prior model in Plug and Play reconstruction approach. Our approach does not require training and are thus able to circumvent ethical issues related with patient training data and are readily deployable in varying noise and measurement sparsity levels. In addition, reconstruction with the BM3D-MSF prior achieves similar reconstruction image quality as fully 3D image priors, but with significantly reduced computational complexity. We test our method on clinical CT data and demonstrate that our approach improves reconstructed image quality.
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