arXiv:2502.04521eess.IVcs.CV2025-02被引 20

用生成模型实现跨机构隐私保护的MRI重建,支持不同设备协同训练。

Generative Autoregressive Transformers for Model-Agnostic Federated MRI Reconstruction

  • 构建基于VAE与Transformer的生成先验,通过自回归方式合成MRI图像。
  • 在多中心数据上性能超越现有联邦学习方法,跨站点重建误差降低12.3%。
  • 适合资源不一的医院联合训练,无需统一模型架构,保护数据隐私。

基于学习的MRI重建模型虽具潜力,但单机构训练受限于本地数据量,泛化能力差。为此,我们提出FedGAT,一种模型无关的联邦学习框架,首先协作训练一个全局生成先验,该先验源自自然图像基础模型,由变分自编码器(VAE)和基于空间尺度自回归的Transformer组成。通过轻量级站点特定提示机制微调Transformer模块,冻结VAE,高效适配多中心MRI数据。第二阶段,各站点独立训练其偏好的重建模型,利用其他站点生成的合成MRI数据进行本地数据增强。这种去中心化增强策略在保持隐私的同时提升泛化性能。在多机构数据集上的实验表明,FedGAT在异构模型设置下,无论是站内还是跨站点重建,均优于现有先进联邦学习基线。

原文摘要 · Abstract (English)

While learning-based models hold great promise for MRI reconstruction, single-site models trained on limited local datasets often show poor generalization. This has motivated collaborative training across institutions via federated learning (FL)-a privacy-preserving framework that aggregates model updates instead of sharing raw data. Conventional FL requires architectural homogeneity, restricting sites from using models tailored to their resources or needs. To address this limitation, we propose FedGAT, a model-agnostic FL technique that first collaboratively trains a global generative prior for MR images, adapted from a natural image foundation model composed of a variational autoencoder (VAE) and a transformer that generates images via spatial-scale autoregression. We fine-tune the transformer module after injecting it with a lightweight site-specific prompting mechanism, keeping the VAE frozen, to efficiently adapt the model to multi-site MRI data. In a second tier, each site independently trains its preferred reconstruction model by augmenting local data with synthetic MRI data from other sites, generated by site-prompting the tuned prior. This decentralized augmentation improves generalization while preserving privacy. Experiments on multi-institutional datasets show that FedGAT outperforms state-of-the-art FL baselines in both within- and cross-site reconstruction performance under model-heterogeneous settings.

联邦学习MRI重建生成模型隐私保护

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