用图像引导融合多尺度特征,提升心脏MRI中左心房分割精度。
Multi-Scale Feature Fusion with Image-Driven Spatial Integration for Left Atrium Segmentation from Cardiac MRI Images
- 基于DINOv2编码器与UNet解码器,融合多尺度特征并重引入输入图像
- 在LAScarQS 2022数据集上达到92.3% Dice和84.1% IoU
- 适合需要高精度心腔分割的临床辅助诊断场景
从延迟钆增强磁共振成像中精确分割左心房(LA)对可视化病变心房结构、诊断和管理心血管疾病至关重要,尤其在房颤消融治疗规划中意义重大。然而,人工分割耗时且存在观察者间差异,亟需自动化方案。类无关基础模型如DINOv2在视觉任务中展现强大特征提取能力,但其缺乏领域特异性与任务适应性,可能导致特征提取过程中空间分辨率下降,影响医学影像中细微解剖结构的捕捉。为此,我们提出一种分割框架:以DINOv2为编码器,结合UNet式解码器,引入多尺度特征融合与输入图像重引入机制,提升分割精度。可学习加权机制动态优化不同编码器层级特征的优先级,提升任务相关性。此外,在解码阶段重新引入输入图像以保留高分辨率空间细节,缓解编码器下采样带来的信息损失。在LAScarQS 2022数据集上的验证表明,该方法在大架构下达到92.3% Dice和84.1% IoU,优于nnUNet基线模型。结果证明该方法在自动化左心房分割领域的有效性。
原文摘要 · Abstract (English)
Accurate segmentation of the left atrium (LA) from late gadolinium-enhanced magnetic resonance imaging plays a vital role in visualizing diseased atrial structures, enabling the diagnosis and management of cardiovascular diseases. It is particularly essential for planning treatment with ablation therapy, a key intervention for atrial fibrillation (AF). However, manual segmentation is time-intensive and prone to inter-observer variability, underscoring the need for automated solutions. Class-agnostic foundation models like DINOv2 have demonstrated remarkable feature extraction capabilities in vision tasks. However, their lack of domain specificity and task-specific adaptation can reduce spatial resolution during feature extraction, impacting the capture of fine anatomical detail in medical imaging. To address this limitation, we propose a segmentation framework that integrates DINOv2 as an encoder with a UNet-style decoder, incorporating multi-scale feature fusion and input image integration to enhance segmentation accuracy. The learnable weighting mechanism dynamically prioritizes hierarchical features from different encoder blocks of the foundation model, optimizing feature selection for task relevance. Additionally, the input image is reintroduced during the decoding stage to preserve high-resolution spatial details, addressing limitations of downsampling in the encoder. We validate our approach on the LAScarQS 2022 dataset and demonstrate improved performance with a 92.3% Dice and 84.1% IoU score for giant architecture compared to the nnUNet baseline model. These findings emphasize the efficacy of our approach in advancing the field of automated left atrium segmentation from cardiac MRI.
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