arXiv:2502.07859eess.IVcs.CV2025-02被引 5

用深度学习自动估算腹部超声中的前列腺体积,无创且准确。

Automatic Prostate Volume Estimation in Transabdominal Ultrasound Images

  • 基于深度学习分割腹部超声的冠状和矢状切面,自动估测前列腺体积。
  • 平均体积误差为-5.5 mL,相对误差在5%至15%之间。
  • 适合需要无创筛查前列腺癌风险的临床场景。

前列腺癌是男性主要健康问题,需精准、易获取的方法实现早期检测与风险分层。前列腺体积(PV)是多因素风险分层的关键参数,通常通过经直肠超声(TRUS)估算。尽管TRUS测量精确,但其侵入性影响患者舒适度。经腹超声(TAUS)提供无创替代方案,但受限于图像质量差、解读复杂及对操作者经验依赖。本研究提出一种基于深度学习的全自动TAUS前列腺体积估算框架,旨在实现精准、无创的风险分层。构建了来自100名患者的TAUS视频数据集,由专家手动勾画前列腺边界并计算直径作为真实标签。该框架整合了轴向与矢状面的前列腺分割模型、自动直径估计及体积计算模块。分割性能采用骰子相关系数(%)和豪斯多夫距离(mm)评估,体积估计性能以体积误差(mL)衡量。结果表明,该框架在TAUS视频上可实现平均体积误差-5.5 mL,平均相对误差介于5%至15%之间。所提深度学习框架在前列腺分割与体积估计方面表现良好,具备实现可靠、无创早期前列腺癌风险分层的潜力。

原文摘要 · Abstract (English)

Prostate cancer is a leading health concern among men, requiring accurate and accessible methods for early detection and risk stratification. Prostate volume (PV) is a key parameter in multivariate risk stratification for early prostate cancer detection, commonly estimated using transrectal ultrasound (TRUS). While TRUS provides precise prostate volume measurements, its invasive nature often compromises patient comfort. Transabdominal ultrasound (TAUS) provides a non-invasive alternative but faces challenges such as lower image quality, complex interpretation, and reliance on operator expertise. This study introduces a new deep-learning-based framework for automatic PV estimation using TAUS, emphasizing its potential to enable accurate and non-invasive prostate cancer risk stratification. A dataset of TAUS videos from 100 individual patients was curated, with manually delineated prostate boundaries and calculated diameters by an expert clinician as ground truth. The introduced framework integrates deep-learning models for prostate segmentation in both axial and sagittal planes, automatic prostate diameter estimation, and PV calculation. Segmentation performance was evaluated using Dice correlation coefficient (%) and Hausdorff distance (mm). Framework's volume estimation capabilities were evaluated on volumetric error (mL). The framework demonstrates that it can estimate PV from TAUS videos with a mean volumetric error of -5.5 mL, which results in an average relative error between 5 and 15%. The introduced framework for automatic PV estimation from TAUS images, utilizing deep learning models for prostate segmentation, shows promising results. It effectively segments the prostate and estimates its volume, offering potential for reliable, non-invasive risk stratification for early prostate detection.

前列腺超声深度学习体积估算

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