arXiv:2502.10662eess.IVcs.LG2025-02

让脑影像模型跨任务通用,无需重新训练

Towards Zero-Shot Task-Generalizable Learning on fMRI

论文配图:Towards Zero-Shot Task-Generalizable Learning on fMRI
图 1 · 摘自论文原文
  • 设计任务感知网络,分离通用编码与任务特异性信息
  • 在多个任务数据上实现零样本迁移,提升泛化能力
  • 可适配任意神经网络,适合脑功能研究者使用

功能磁共振成像(fMRI)通过测量血氧水平依赖信号,在研究脑功能和神经疾病中日益重要。相比静息态fMRI,任务态fMRI在受试者执行特定任务时采集,能增强与任务相关的脑活动信号,信息量更丰富。然而,由于任务设计多样,不同任务的fMRI数据难以融合以训练通用模型。为此,我们提出监督式任务感知网络TA-GAT,联合学习通用编码器与任务特异性上下文信息。编码器生成的嵌入与学习到的上下文信息结合,作为输入供给多个下游任务模块。我们认为,该任务感知架构可无缝嵌入任意神经网络,将fMRI任务先验知识融入功能性脑模式捕捉中。

原文摘要 · Abstract (English)

Functional MRI measuring BOLD signal is an increasingly important imaging modality in studying brain functions and neurological disorders. It can be acquired in either a resting-state or a task-based paradigm. Compared to resting-state fMRI, task-based fMRI is acquired while the subject is performing a specific task designed to enhance study-related brain activities. Consequently, it generally has more informative task-dependent signals. However, due to the variety of task designs, it is much more difficult than in resting state to aggregate task-based fMRI acquired in different tasks to train a generalizable model. To resolve this complication, we propose a supervised task-aware network TA-GAT that jointly learns a general-purpose encoder and task-specific contextual information. The encoder-generated embedding and the learned contextual information are then combined as input to multiple modules for performing downstream tasks. We believe that the proposed task-aware architecture can plug-and-play in any neural network architecture to incorporate the prior knowledge of fMRI tasks into capturing functional brain patterns.

fMRI脑影像零样本

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