用奖励机制自动优化显微镜图像分析,减少人工干预。
Rewards-based image analysis in microscopy
- 以奖励驱动替代传统人工设计流程,实现自动化数据表示。
- 在扫描探针和电子显微镜中验证了跨任务强迁移能力。
- 适合需要可解释性与低标注成本的科研图像分析场景。
成像与高光谱数据分析是生物、医学、化学和物理领域进步的核心。核心挑战在于将高分辨率或高维数据转化为可解释的表征,以揭示系统内在的物理或化学特性。传统分析依赖专家设计的多步骤流程,如去噪、特征提取、聚类、降维及基于物理的解卷积,或使用机器学习方法加速单个步骤。但这些方法通常需大量人工干预,包括超参数调优和数据标注。实现科学成像更高程度的自主性,需设计有效的奖励驱动工作流,引导算法生成最优数据表征以支持人类或自动化决策。本文讨论近期在图像分析中奖励驱动工作流的进展,其捕捉人类推理的关键要素,并在多种任务间表现出强泛化能力。奖励驱动方法推动从监督式黑箱模型向可解释的无监督优化转变,已在扫描探针显微镜和电子显微镜中得到验证。这类框架适用于分类、回归、结构-性能映射及通用高光谱数据处理等广泛场景。
原文摘要 · Abstract (English)
Imaging and hyperspectral data analysis is central to progress across biology, medicine, chemistry, and physics. The core challenge lies in converting high-resolution or high-dimensional datasets into interpretable representations that enable insight into the underlying physical or chemical properties of a system. Traditional analysis relies on expert-designed, multistep workflows, such as denoising, feature extraction, clustering, dimensionality reduction, and physics-based deconvolution, or on machine learning (ML) methods that accelerate individual steps. Both approaches, however, typically demand significant human intervention, including hyperparameter tuning and data labeling. Achieving the next level of autonomy in scientific imaging requires designing effective reward-based workflows that guide algorithms toward best data representation for human or automated decision-making. Here, we discuss recent advances in reward-based workflows for image analysis, which capture key elements of human reasoning and exhibit strong transferability across various tasks. We highlight how reward-driven approaches enable a shift from supervised black-box models toward explainable, unsupervised optimization on the examples of Scanning Probe and Electron Microscopies. Such reward-based frameworks are promising for a broad range of applications, including classification, regression, structure-property mapping, and general hyperspectral data processing.
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