用扩散模型生成超声图像增强数据,提升心脏分割模型泛化能力
Generative augmentations for improved cardiac ultrasound segmentation using diffusion models
- 基于扩散模型生成逼真超声图像,扩充训练数据多样性
- 外部数据测试时豪斯多夫距离改善超20毫米,射血分数估计误差降低20%
- 无需修改模型即可提升性能,适合医疗影像数据稀缺场景
当前心脏超声分割研究面临标注数据少且标注规范不一的挑战,导致模型难以泛化到外部数据集。本文利用扩散模型生成高质量图像增广数据,显著提升训练数据多样性,从而增强分割模型的泛化能力,无需额外标注。增广效果在视觉测试中经专家验证无法区分真实与生成图像。在内部数据集训练、外部数据集测试条件下,豪斯多夫距离改善超过20毫米;在分布外病例中,自动射血分数估计的一致性限度改善达绝对射血分数值的20%。所有提升均来自生成增广带来的数据变异性增强,未改动基础模型架构。相关工具已开源,项目地址:https://github.com/GillesVanDeVyver/EchoGAINS。
原文摘要 · Abstract (English)
One of the main challenges in current research on segmentation in cardiac ultrasound is the lack of large and varied labeled datasets and the differences in annotation conventions between datasets. This makes it difficult to design robust segmentation models that generalize well to external datasets. This work utilizes diffusion models to create generative augmentations that can significantly improve diversity of the dataset and thus the generalisability of segmentation models without the need for more annotated data. The augmentations are applied in addition to regular augmentations. A visual test survey showed that experts cannot clearly distinguish between real and fully generated images. Using the proposed generative augmentations, segmentation robustness was increased when training on an internal dataset and testing on an external dataset with an improvement of over 20 millimeters in Hausdorff distance. Additionally, the limits of agreement for automatic ejection fraction estimation improved by up to 20% of absolute ejection fraction value on out of distribution cases. These improvements come exclusively from the increased variation of the training data using the generative augmentations, without modifying the underlying machine learning model. The augmentation tool is available as an open source Python library at https://github.com/GillesVanDeVyver/EchoGAINS.
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