脑基础模型统一处理多种神经信号,推动脑科学发现
Brain Foundation Models: A Survey on Advancements in Neural Signal Processing and Brain Discovery
- 首次定义脑基础模型,构建统一建模框架
- 支持跨任务、跨模态泛化,提升神经信号处理能力
- 适合神经科学与人工智能交叉研究者参考
脑基础模型(BFMs)作为计算神经科学中的新兴范式,为处理多种脑相关任务中的神经信号提供了革命性框架。这些模型采用大规模预训练技术,可在不同场景、任务和模态间有效泛化,突破了传统人工智能方法在理解复杂脑数据时的局限。通过利用预训练模型的能力,BFMs实现了神经数据处理的统一化,促进了神经科学中的高级分析与发现。本文首次系统定义了脑基础模型,提出了构建与应用的清晰框架,梳理了其核心原理与方法论,揭示了其对神经信号处理领域的变革作用。本综述全面回顾了最新进展,涵盖方法创新、应用新视角及领域挑战。重点指出未来需解决的关键问题:提升脑数据质量、优化模型架构以增强泛化能力、提高训练效率,以及加强模型在实际应用中的可解释性与鲁棒性。
原文摘要 · Abstract (English)
Brain foundation models (BFMs) have emerged as a transformative paradigm in computational neuroscience, offering a revolutionary framework for processing diverse neural signals across different brain-related tasks. These models leverage large-scale pre-training techniques, allowing them to generalize effectively across multiple scenarios, tasks, and modalities, thus overcoming the traditional limitations faced by conventional artificial intelligence (AI) approaches in understanding complex brain data. By tapping into the power of pretrained models, BFMs provide a means to process neural data in a more unified manner, enabling advanced analysis and discovery in the field of neuroscience. In this survey, we define BFMs for the first time, providing a clear and concise framework for constructing and utilizing these models in various applications. We also examine the key principles and methodologies for developing these models, shedding light on how they transform the landscape of neural signal processing. This survey presents a comprehensive review of the latest advancements in BFMs, covering the most recent methodological innovations, novel views of application areas, and challenges in the field. Notably, we highlight the future directions and key challenges that need to be addressed to fully realize the potential of BFMs. These challenges include improving the quality of brain data, optimizing model architecture for better generalization, increasing training efficiency, and enhancing the interpretability and robustness of BFMs in real-world applications.
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