用生成模型合成脑电数据并自动提取特征,减少人工干预。
A Deep Generative Model for Resting-State EEG Synthesis and Transferable Representation Learning
- 用对抗训练加自监督重建,直接从原始脑电信号学特征。
- 生成数据在频带功率、连接性上接近真实数据,精度达0.91/0.67。
- 学到的特征可迁移分类,比纯原始数据模型更强,省资源。
静息态脑电提供对自发脑活动的无创观测,但其模式提取常受限于高质量数据稀缺和依赖人工特征工程。生成对抗网络(GAN)能直接从原始数据合成神经信号并学习可迁移表征,这一双重能力在脑电研究中仍待深入探索。本文提出REST-GAN,一种基于GAN的静息态脑电框架,结合对抗训练与辅助自监督重建目标,实现信号合成与无监督特征提取。尽管仅在原始时域信号上训练,未使用频域或电极拓扑监督,生成的时间序列仍重现了真实脑电的关键时序、频谱及连通性特征。在频带功率特征空间中,生成样本在睁眼(EO: 0.91/0.67)与闭眼(EC: 0.87/0.65)条件下均表现出高精确率与召回率;各频段组平均谱相干矩阵与真实数据间均方绝对差约为0.01–0.03。模型判别器学习到的表征可迁移至独立的静息态人口统计分类任务,性能优于直接在原始脑电上训练的模型,并达到近期脑电基础模型的竞争力,且所需训练数据与计算资源显著更少。结果表明,生成模型不仅可用作脑电信号生成器,还可作为高效的无监督特征提取器,有望推动更数据高效的脑电分析,减少对人工特征工程的依赖。REST-GAN代码已开源:https://github.com/Yeganehfrh/REST-GAN。
原文摘要 · Abstract (English)
Resting-state EEG provides a non-invasive view of spontaneous brain activity, but extracting meaningful patterns is often limited by scarce high-quality data and reliance on manually engineered features. Generative adversarial networks (GANs) can synthesize neural signals and learn transferable representations directly from raw data, a dual capability that remains underexplored in EEG research. Here, we introduce REST-GAN, a GAN-based framework for resting-state EEG that combines adversarial training with an auxiliary self-supervised reconstruction objective to support signal synthesis and unsupervised feature extraction. Although trained only on raw time-domain signals, without explicit frequency-domain or sensor-topographic supervision, the generated time series reproduced key temporal, spectral, and connectivity properties of real EEG. In band-power feature space, generated samples showed high precision and recall across eyes-open and eyes-closed conditions (EO: 0.91/0.67; EC: 0.87/0.65), while group-average spectral coherence matrices showed low mean absolute differences from real data across frequency bands (~0.01-0.03). The representations learned by the model's critic transferred to independent resting-state demographic classification tasks, outperforming models trained directly on raw EEG and showing competitive performance relative to a recent EEG foundation model, while requiring substantially less training data and computational resources. These findings highlight a computationally efficient, architecture-driven strategy in which generative models serve not only as EEG signal generators, but also as unsupervised feature extractors. This approach may support more data-efficient EEG analysis while reducing reliance on manual feature engineering. The implementation code for REST-GAN is available at: https://github.com/Yeganehfrh/REST-GAN.
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