用高斯随机场表示患者信息,提升糖尿病足溃疡分割精度
Gaussian Random Fields as an Abstract Representation of Patient Metadata for Multimodal Medical Image Segmentation
- 将患者元数据转为高斯随机场嵌入多模态分割流程
- 在Diabetic Foot Ulcer Challenge 2022上IoU提升至0.4890,Dice达0.6137
- 适合关注医疗影像融合与患者个体化建模的研究者
近年来,糖尿病患者慢性伤口发生率持续上升,治疗困难且成本高昂,已成为全球医疗系统的重要负担。此类伤口常导致感染,严重影响生活质量并增加死亡风险。基于深度学习的检测与监测方法有望减轻患者与临床负担。本文提出一种新型多模态分割方法,将患者元数据以高斯随机场形式引入训练流程。实验表明,针对不同元数据类别分别训练模型后,通过距离变换平均融合预测掩码,性能显著提升。在糖尿病足溃疡挑战赛2022测试集上,相较于基线(交并比0.4670,Dice系数0.5908),本方法分别提升0.0220和0.0229。本文首次聚焦将患者数据融入慢性伤口分割工作流,结果表明按元数据类别独立训练再融合可带来明显增益。所有源代码已公开于:https://github.com/mmu-dermatology-research/multimodal-grf
原文摘要 · Abstract (English)
The growing rate of chronic wound occurrence, especially in patients with diabetes, has become a concerning trend in recent years. Chronic wounds are difficult and costly to treat, and have become a serious burden on health care systems worldwide. Chronic wounds can have devastating consequences for the patient, with infection often leading to reduced quality of life and increased mortality risk. Innovative deep learning methods for the detection and monitoring of such wounds have the potential to reduce the impact to both patient and clinician. We present a novel multimodal segmentation method which allows for the introduction of patient metadata into the training workflow whereby the patient data are expressed as Gaussian random fields. Our results indicate that the proposed method improved performance when utilising multiple models, each trained on different metadata categories. Using the Diabetic Foot Ulcer Challenge 2022 test set, when compared to the baseline results (intersection over union = 0.4670, Dice similarity coefficient = 0.5908) we demonstrate improvements of +0.0220 and +0.0229 for intersection over union and Dice similarity coefficient respectively. This paper presents the first study to focus on integrating patient data into a chronic wound segmentation workflow. Our results show significant performance gains when training individual models using specific metadata categories, followed by average merging of prediction masks using distance transforms. All source code for this study is available at: https://github.com/mmu-dermatology-research/multimodal-grf
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