arXiv:2503.10741cs.LGcs.AI2025-03被引 1

用可解释机器学习预测身体畸形障碍治疗反应,发现治疗可信度最关键。

Predicting Treatment Response in Body Dysmorphic Disorder with Interpretable Machine Learning

  • 采用可解释机器学习模型分析治疗反应
  • 治疗可信度比症状严重程度更关键,能预测疗效
  • 揭示可信度阈值,适合临床制定个性化干预

身体畸形障碍(BDD)是一种高患病率且常被漏诊的疾病,特征为持续、侵入性的外观缺陷感知。本研究通过多种机器学习方法预测治疗反应与缓解情况,重点强调模型可解释性以确保临床价值。在所考察的模型中,治疗可信度成为最强预测因子,优于传统指标如基线症状严重度或共病状况。尽管简单模型(如逻辑回归、支持向量机)表现良好,决策树分析揭示了可信度评分中的临床可解释阈值,可作为医生调整治疗或分配资源的实用参考。研究还将发现置于BDD领域更广泛文献中,涵盖技术疗法、数字干预及治疗参与的心理社会因素。大量参考文献将结果置于当前关于BDD患病率、自杀风险与数字创新的研究背景中。工作表明,结合严谨统计方法与透明机器学习模型具有潜力。通过系统识别可改变的预测因子(如治疗可信度),提出通往更精准、个性化和高效干预的新路径。

原文摘要 · Abstract (English)

Body Dysmorphic Disorder (BDD) is a highly prevalent and frequently underdiagnosed condition characterized by persistent, intrusive preoccupations with perceived defects in physical appearance. In this extended analysis, we employ multiple machine learning approaches to predict treatment outcomes -- specifically treatment response and remission -- with an emphasis on interpretability to ensure clinical relevance and utility. Across the various models investigated, treatment credibility emerged as the most potent predictor, surpassing traditional markers such as baseline symptom severity or comorbid conditions. Notably, while simpler models (e.g., logistic regression and support vector machines) achieved competitive predictive performance, decision tree analyses provided unique insights by revealing clinically interpretable threshold values in credibility scores. These thresholds can serve as practical guideposts for clinicians when tailoring interventions or allocating treatment resources. We further contextualize our findings within the broader literature on BDD, addressing technology-based therapeutics, digital interventions, and the psychosocial determinants of treatment engagement. An extensive array of references situates our results within current research on BDD prevalence, suicidality risks, and digital innovation. Our work underscores the potential of integrating rigorous statistical methodologies with transparent machine learning models. By systematically identifying modifiable predictors -- such as treatment credibility -- we propose a pathway toward more targeted, personalized, and ultimately efficacious interventions for individuals with BDD.

机器学习心理障碍可解释性个性化医疗

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