用AI自动构建患者血管模型,加速血流模拟临床应用
AI-Powered Automated Model Construction for Patient-Specific CFD Simulations of Aortic Flows
- 深度学习统一分割与表面优化,实现全自动建模
- 在公开数据集上达到顶尖分割与网格质量,耗时大幅降低
- 适合心血管研究与临床模拟,提升建模效率与可靠性
基于图像的建模对理解心血管血流动力学及推进心血管疾病诊断治疗至关重要。构建患者特异性血管模型仍需大量人工操作,易出错且耗时,限制了其临床应用。本研究提出一种深度学习框架,可从医学影像自动创建适用于仿真的血管模型。该框架整合了高精度体素级血管分割模块与基于医学图像数据指导的解剖一致、无监督表面精修模块。通过将体素分割与表面变形统一为单一流程,解决了现有方法的关键局限,显著提升了几何精度与计算效率。在公开数据集上的评估显示,该方法在分割与网格质量方面达到当前最优水平,同时大幅减少人工干预和处理时间。本工作推动了基于图像的计算建模的可扩展性与可靠性,为临床与科研应用提供了更广泛支持。
原文摘要 · Abstract (English)
Image-based modeling is essential for understanding cardiovascular hemodynamics and advancing the diagnosis and treatment of cardiovascular diseases. Constructing patient-specific vascular models remains labor-intensive, error-prone, and time-consuming, limiting their clinical applications. This study introduces a deep-learning framework that automates the creation of simulation-ready vascular models from medical images. The framework integrates a segmentation module for accurate voxel-based vessel delineation with a surface deformation module that performs anatomically consistent and unsupervised surface refinements guided by medical image data. By unifying voxel segmentation and surface deformation into a single cohesive pipeline, the framework addresses key limitations of existing methods, enhancing geometric accuracy and computational efficiency. Evaluated on publicly available datasets, the proposed approach demonstrates state-of-the-art performance in segmentation and mesh quality while significantly reducing manual effort and processing time. This work advances the scalability and reliability of image-based computational modeling, facilitating broader applications in clinical and research settings.
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