arXiv:2503.13477q-bio.TOcs.AI2025-03被引 3

用关键点检测自动分析牙周骨流失,提升诊断一致性。

Periodontal Bone Loss Analysis via Keypoint Detection With Heuristic Post-Processing

  • 通过启发式后处理对齐关键点与牙齿边界,改善定位精度。
  • 平均PRCK^{0.05}提升0.028,但粗粒度指标略有下降。
  • 适用于临床可解释的牙周病评估,减轻医生工作量。

本研究提出一种深度学习框架与标注方法,用于自动检测牙周骨流失的关键点、相关病变及分期。收集192张根尖片,采用无阶段依赖的标注方式,标记临床相关关键点,无论疾病是否存在或程度如何。提出一种启发式后处理模块,利用辅助实例分割模型将预测关键点对齐至牙体边界。设计了百分比相对正确关键点(PRCK)作为牙科影像领域的评估指标。四种源姿态估计模型经微调应用于本任务。后处理提升了细粒度定位,使平均PRCK^{0.05}提高0.028,但粗粒度指标中PRCK^{0.25}和PRCK^{0.5}分别下降0.0523和0.0345。辅助分割在过滤阶段1目标检测结果后表现优异。牙周分期检测尚可,近中与远中最佳Dice分数分别为0.508和0.489;而分叉受累和牙周膜间隙增宽任务因正样本稀少仍具挑战。验证集与外部测试集性能相似,表明系统具备可扩展性。该标注方法支持无阶段训练,部分任务中不同严重程度样本分布均衡。PRCK为通用姿态评估指标提供领域适配替代方案,启发式后处理能持续修正不合理预测,偶有灾难性失败。整体框架证明了临床可解释牙周骨流失评估的可行性,有望降低诊断差异并减轻医生负担。

原文摘要 · Abstract (English)

This study proposes a deep learning framework and annotation methodology for the automatic detection of periodontal bone loss landmarks, associated conditions, and staging. 192 periapical radiographs were collected and annotated with a stage agnostic methodology, labelling clinically relevant landmarks regardless of disease presence or extent. We propose a heuristic post-processing module that aligns predicted keypoints to tooth boundaries using an auxiliary instance segmentation model. An evaluation metric, Percentage of Relative Correct Keypoints (PRCK), is proposed to capture keypoint performance in dental imaging domains. Four donor pose estimation models were adapted with fine-tuning for our keypoint problem. Post-processing improved fine-grained localisation, raising average PRCK^{0.05} by +0.028, but reduced coarse performance for PRCK^{0.25} by -0.0523 and PRCK^{0.5} by -0.0345. Orientation estimation shows excellent performance for auxiliary segmentation when filtered with either stage 1 object detection model. Periodontal staging was detected sufficiently, with the best mesial and distal Dice scores of 0.508 and 0.489, while furcation involvement and widened periodontal ligament space tasks remained challenging due to scarce positive samples. Scalability is implied with similar validation and external set performance. The annotation methodology enables stage agnostic training with balanced representation across disease severities for some detection tasks. The PRCK metric provides a domain-specific alternative to generic pose metrics, while the heuristic post-processing module consistently corrected implausible predictions with occasional catastrophic failures. The proposed framework demonstrates the feasibility of clinically interpretable periodontal bone loss assessment, with potential to reduce diagnostic variability and clinician workload.

牙周病关键点检测医学影像后处理

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