arXiv:2503.19945eess.IVcs.AI2025-03被引 4

多视角分析提升乳腺癌筛查准确率,实验验证了新方法的优越性。

Optimizing Breast Cancer Detection in Mammograms: A Comprehensive Study of Transfer Learning, Resolution Reduction, and Multi-View Classification

  • 采用多视角联合分析,融合不同投影像,提升诊断一致性。
  • 在CBIS-DDSM上单视图AUC达0.8343,多视图达0.8658,刷新纪录。
  • 方法对图像质量鲁棒,适合临床部署与模型优化研究者参考。

乳腺钼靶成像仍是早期发现乳腺癌的核心手段。近年来人工智能推动了辅助诊断技术的发展,从局部切片分类演进至全图分析,再到联合分析互补投影的多视角架构。然而关键问题仍待解答:(1)切片分类器的作用;(2)自然图像预训练主干网络的可迁移性;(3)学习型缩放相比传统下采样的优势;(4)多视角融合的贡献;(5)结果在不同图像质量下的鲁棒性。本研究系统回答上述五个问题。实验表明,在CBIS-DDSM数据集上,单视图AUC从0.8153提升至0.8343,多视图从0.8483升至0.8658;在完整VinDr-Mammo数据集上,多视图相较单视图提升0.0492 AUC,达到0.8511。新增对比方法显示,从单视图扩展至多视图带来0.0217 AUC增益。结果确立了新基准,证明多视角架构在钼靶解读中的显著优势。研究还为模型设计与迁移学习提供可解释洞见,助力更精准可靠的筛查工具发展。推理代码与训练模型已公开于https://github.com/dpetrini/multiple-view。

原文摘要 · Abstract (English)

Mammography, an X-ray-based imaging technique, remains central to the early detection of breast cancer. Recent advances in artificial intelligence have enabled increasingly sophisticated computer-aided diagnostic methods, evolving from patch-based classifiers to whole-image approaches and then to multi-view architectures that jointly analyze complementary projections. Despite this progress, several critical questions remain unanswered. In this study, we systematically investigate these issues by addressing five key research questions: (1) the role of patch classifiers in performance, (2) the transferability of natural-image-trained backbones, (3) the advantages of learn-to-resize over conventional downscaling, (4) the contribution of multi-view integration, and (5) the robustness of findings across varying image quality. Beyond benchmarking, our experiments demonstrate clear performance gains over prior work. For the CBIS-DDSM dataset, we improved single-view AUC from 0.8153 to 0.8343, and multiple-view AUC from 0.8483 to 0.8658. Using a new comparative method, we also observed a 0.0217 AUC increase when extending from single to multiple-view analysis. On the complete VinDr-Mammo dataset, the multiple-view approach further improved results, achieving a 0.0492 AUC increase over single view and reaching 0.8511 AUC overall. These results establish new state-of-the-art benchmarks, providing clear evidence of the advantages of multi-view architectures for mammogram interpretation. Beyond performance, our analysis offers principled insights into model design and transfer learning strategies, contributing to the development of more accurate and reliable breast cancer screening tools. The inference code and trained models are publicly available at https://github.com/dpetrini/multiple-view.

乳腺癌检测多视角迁移学习医学影像

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