arXiv:2503.23072cs.LG2025-03中稿 · WWW'25 short paper…

用轨迹编码提升住院期间化验预测准确率

TRACE: Intra-visit Clinical Event Nowcasting via Effective Patient Trajectory Encoding

  • 基于Transformer构建患者轨迹编码模型,融合时间衰减与周期性特征
  • 在两个大规模EHR数据集上显著优于现有方法,化验预测更准
  • 适合临床实时决策支持系统开发人员参考

电子健康记录(EHR)已成为医疗预测任务的重要资源。然而,现有方法多聚焦于跨就诊事件预测,忽视了住院期间的即时预测(intra-visit nowcasting)价值。本文提出在单次住院过程中预测实验室检测结果的任务,并研究此前被忽视的实验室数据。我们提出TRACE模型,一种基于Transformer的临床事件即时预测方法,通过创新的时间戳嵌入编码患者轨迹,有效处理长序列并捕捉时序依赖关系,该嵌入融合了数据的衰减特性与周期模式。此外,引入平滑掩码进行去噪,增强模型鲁棒性。在两个大规模EHR数据集上的实验表明,该模型显著优于现有方法,展现出通过更精准的化验预测提升患者照护质量的潜力。代码已公开于https://github.com/Amehi/TRACE。

原文摘要 · Abstract (English)

Electronic Health Records (EHR) have become a valuable resource for a wide range of predictive tasks in healthcare. However, existing approaches have largely focused on inter-visit event predictions, overlooking the importance of intra-visit nowcasting, which provides prompt clinical insights during an ongoing patient visit. To address this gap, we introduce the task of laboratory measurement prediction within a hospital visit. We study the laboratory data that, however, remained underexplored in previous work. We propose TRACE, a Transformer-based model designed for clinical event nowcasting by encoding patient trajectories. TRACE effectively handles long sequences and captures temporal dependencies through a novel timestamp embedding that integrates decay properties and periodic patterns of data. Additionally, we introduce a smoothed mask for denoising, improving the robustness of the model. Experiments on two large-scale electronic health record datasets demonstrate that the proposed model significantly outperforms previous methods, highlighting its potential for improving patient care through more accurate laboratory measurement nowcasting. The code is available at https://github.com/Amehi/TRACE.

临床预测TransformerEHR化验预测

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