提出三阶段框架,精准提取冠状动脉完整树状结构。
A topology-preserving three-stage framework for fully-connected coronary artery extraction
- 分三步:分割、中心线重连、缺失血管重建
- 在ASOCA和PDSCA数据集上达88.53%和85.07%的Dice分数
- 适合医学影像分析与心血管疾病辅助诊断研究者
冠状动脉提取是冠心病计算机辅助诊断的关键前提。由于远端细小血管、迂曲拓扑结构及对比度不足等因素,现有方法常导致过分割或欠分割。为此,本文提出一种拓扑保持的三阶段全连接冠状动脉提取框架,包含血管分割、中心线重连和缺失血管重建。首先,在分割阶段引入新型中心线增强损失;其次,针对断裂血管段,提出正则化行走算法,结合距离、中心线分类概率与方向余弦相似性实现中心线重连;最后,采用隐式神经表示与隐式建模重建缺失血管几何结构。实验表明,该框架在ASOCA与PDSCA数据集上分别取得88.53%与85.07%的Dice分数,以及1.07mm和1.63mm的豪斯多夫距离。代码将公开于https://github.com/YH-Qiu/CorSegRec。
原文摘要 · Abstract (English)
Coronary artery extraction is a crucial prerequisite for computer-aided diagnosis of coronary artery disease. Accurately extracting the complete coronary tree remains challenging due to several factors, including presence of thin distal vessels, tortuous topological structures, and insufficient contrast. These issues often result in over-segmentation and under-segmentation in current segmentation methods. To address these challenges, we propose a topology-preserving three-stage framework for fully-connected coronary artery extraction. This framework includes vessel segmentation, centerline reconnection, and missing vessel reconstruction. First, we introduce a new centerline enhanced loss in the segmentation process. Second, for the broken vessel segments, we further propose a regularized walk algorithm to integrate distance, probabilities predicted by a centerline classifier, and directional cosine similarity, for reconnecting the centerlines. Third, we apply implicit neural representation and implicit modeling, to reconstruct the geometric model of the missing vessels. Experimental results show that our proposed framework outperforms existing methods, achieving Dice scores of 88.53\% and 85.07\%, with Hausdorff Distances (HD) of 1.07mm and 1.63mm on ASOCA and PDSCA datasets, respectively. Code will be available at https://github.com/YH-Qiu/CorSegRec.
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