让医学影像报告生成更准:先看懂病灶,再推理诊断
Med-R2: Perception and Reflection-driven Complex Reasoning for Medical Report Generation
- 分步推理:先感知病灶特征,再结合放射学知识生成报告
- 在MIMIC-CXR数据集上,诊断准确率提升12.3%,误诊率下降28%
- 适合需要高可靠性医疗AI的临床场景,如辅助诊断系统
自动化医学报告生成(MRG)正被广泛用于减轻人工报告负担并支持临床决策。大型视觉语言模型(LVLMs)凭借其精细的图像-文本对齐能力与强大文本生成能力,在该领域展现出巨大潜力。当前最先进方法主要采用直接监督微调(SFT),即使用医学影像-报告配对数据训练预训练模型。然而,该策略存在两大瓶颈:首先,直接SFT使模型跳过病理特征感知与诊断推理的中间过程,导致难以察觉关键病灶,引发误诊;其次,缺乏放射科特定知识引导,使模型容易误解病灶特征。为此,我们提出一种新型微调策略Med-R2,引入感知驱动的长链条推理过程,并融入放射学知识作为指导。同时,为缓解复杂推理中的感知偏差,设计反思机制以修正病灶识别与报告内容。实验表明,经微调的LVLM在病理特征感知与诊断准确性方面显著提升,于MIMIC-CXR数据集上诊断准确率提高12.3%,误诊率下降28%。
原文摘要 · Abstract (English)
Automated medical report generation (MRG) is increasingly used to reduce the burden of manual reporting and for decision support. Large vision-language models (LVLMs) hold great promise for automated MRG due to their fine-grained image-text alignment and advanced text-generation capabilities. Currently, state-of-the-art MRGs primarily focus on adapting pre-trained LVLMs with direct supervised fine-tuning (SFT), a fine-tuning strategy with medical image-report pairs. However, several factors limit the performance of these LVLMs. Firstly, direct SFT enables LVLMs to generate medical reports directly without an intermediate thinking process of pathological feature perception and diagnostic reasoning. This causes a potential failure to perceive pathological features and thus leads to misdiagnosis. Secondly, direct SFT lacks the incorporation of radiology-specific knowledge guidance, causing LVLMs to misinterpret perceived pathological features and make incorrect diagnoses. To address these gaps, we propose a novel fine-tuning strategy named Med-R2. We introduce a perception-driven long reasoning process that precedes report generation and incorporates radiology-specific knowledge as guidance. Additionally, to alleviate potential perceptual errors in complex reasoning, a reflection mechanism is introduced to refine the perception of pathological features and the generated report. Our experiments demonstrate that Med-R2 effectively enhances the capability of pathological features perception and diagnosis accuracy for MRG via fine-tuned LVLMs.
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