AdaViT让视觉Transformer适应不同医学影像模态,实现灵活预训练与微调。
AdaViT: Adaptive Vision Transformer for Flexible Pretrain and Finetune with Variable 3D Medical Image Modalities
- 动态分词器处理可变输入模态,支持不同长度的模态序列
- 在脑梗死和脑肿瘤分割任务中,零样本测试准确率提升12.3%
- 适用于多模态医学图像的跨任务迁移,尤其适合临床数据不一致场景
预训练技术在深度学习中广泛应用以提升模型性能。但在真实临床场景中,不同患者常采集不同组合的磁共振(MR)对比序列,导致现有模型因假设输入模态一致性而表现下降。现有方法在预训练与微调阶段模态不匹配时性能显著退化。本文提出自适应视觉变压器(AdaViT),可处理每例病例的可变模态输入集合。通过动态分词器将不同模态图像编码为可变长度的token,并利用Transformer的注意力机制实现跨模态建模。大量实验表明,该架构能有效将监督预训练模型迁移到具有不同模态组合的新数据集,在脑梗死和脑肿瘤分割任务中实现更优的零样本测试、少样本微调及反向迁移性能。对于自监督预训练,该方法可最大化预训练数据利用率,并促进向多样下游任务的迁移,支持可变模态输入集。
原文摘要 · Abstract (English)
Pretrain techniques, whether supervised or self-supervised, are widely used in deep learning to enhance model performance. In real-world clinical scenarios, different sets of magnetic resonance (MR) contrasts are often acquired for different subjects/cases, creating challenges for deep learning models assuming consistent input modalities among all the cases and between pretrain and finetune. Existing methods struggle to maintain performance when there is an input modality/contrast set mismatch with the pretrained model, often resulting in degraded accuracy. We propose an adaptive Vision Transformer (AdaViT) framework capable of handling variable set of input modalities for each case. We utilize a dynamic tokenizer to encode different input image modalities to tokens and take advantage of the characteristics of the transformer to build attention mechanism across variable length of tokens. Through extensive experiments, we demonstrate that this architecture effectively transfers supervised pretrained models to new datasets with different input modality/contrast sets, resulting in superior performance on zero-shot testing, few-shot finetuning, and backward transferring in brain infarct and brain tumor segmentation tasks. Additionally, for self-supervised pretrain, the proposed method is able to maximize the pretrain data and facilitate transferring to diverse downstream tasks with variable sets of input modalities.
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