arXiv:2504.06811cs.CVcs.LG2025-04被引 1

用切比雪夫多项式增强CNN,提升肺结节良恶性判断准确率

Hybrid CNN with Chebyshev Polynomial Expansion for Medical Image Analysis

  • 将切比雪夫多项式嵌入CNN层,捕捉更精细的空间频域特征
  • 在LUNA16和LIDC-IDRI数据集上,准确率、敏感性和特异性均显著提升
  • 适合医学影像智能诊断研究者,尤其关注肺结节检测的场景

肺癌是全球癌症死亡的主要原因之一,早期精准诊断对改善患者预后至关重要。基于CT扫描的肺结节自动检测因结节大小、形状、纹理和位置的差异而极具挑战性。传统卷积神经网络(CNN)在医学图像分析中表现良好,但其对细微空间-光谱变化的捕捉能力有限,制约了复杂诊断场景下的性能。本文提出一种新型混合深度学习架构,将切比雪夫多项式展开引入CNN层,以增强模型表达能力并改善解剖结构表征。所提出的Chebyshev-CNN利用切比雪夫多项式的正交性与递推特性,更精准地提取高频特征,并以更高保真度逼近复杂非线性函数。该模型在基准肺癌影像数据集LUNA16和LIDC-IDRI上进行训练与评估,显著优于传统CNN方法,在区分肺结节良恶性方面表现优异。定量结果表明,模型在准确率、敏感性和特异性上均有明显提升。该基于多项式谱逼近的深度学习集成框架为自动化医疗诊断提供了稳健方案,具有广泛应用于临床决策支持系统的潜力。

原文摘要 · Abstract (English)

Lung cancer remains one of the leading causes of cancer-related mortality worldwide, with early and accurate diagnosis playing a pivotal role in improving patient outcomes. Automated detection of pulmonary nodules in computed tomography (CT) scans is a challenging task due to variability in nodule size, shape, texture, and location. Traditional Convolutional Neural Networks (CNNs) have shown considerable promise in medical image analysis; however, their limited ability to capture fine-grained spatial-spectral variations restricts their performance in complex diagnostic scenarios. In this study, we propose a novel hybrid deep learning architecture that incorporates Chebyshev polynomial expansions into CNN layers to enhance expressive power and improve the representation of underlying anatomical structures. The proposed Chebyshev-CNN leverages the orthogonality and recursive properties of Chebyshev polynomials to extract high-frequency features and approximate complex nonlinear functions with greater fidelity. The model is trained and evaluated on benchmark lung cancer imaging datasets, including LUNA16 and LIDC-IDRI, achieving superior performance in classifying pulmonary nodules as benign or malignant. Quantitative results demonstrate significant improvements in accuracy, sensitivity, and specificity compared to traditional CNN-based approaches. This integration of polynomial-based spectral approximation within deep learning provides a robust framework for enhancing automated medical diagnostics and holds potential for broader applications in clinical decision support systems.

医学影像肺结节检测深度学习切比雪夫

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